Gorham–Stout syndrome, the challenge in diagnosis and unique in treatment: a case report

Journal of Medical Case Reports

Case Report

Seyyed Hadi Kalantar¹  Nima Bagheri¹  Sadegh Saberi¹  Seyyed Saeed Khabiri¹  Hana Saffar² 

[1] Department of Orthopedic Surgery, Joint Reconstruction Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Keshavarz Boulevard, 1419733141, Tehran, Iran;Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran;

关键词: Gorham-Stout syndrome;    Bone resorption;    Endoprosthesis;    Total femur replacement;   

DOI  :  10.1186/s13256-023-04094-7

 received in 2023-03-23, accepted in 2023-07-21,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundGorham–Stout disease is a rare condition with fewer than 400 reported cases in the literature. The presentation of Gorham–Stout disease varies on the basis of location, extent, fracture, and accompanying symptoms. It lacks a specific histopathological appearance but is characterized by vascular changes and the absence of cellular atypia.Case presentationThis article presents a case study of a 16-year-old Persian boy with an entire femur with Gorham–Stout disease, highlighting the difficulties in managing this condition. The lack of a clear diagnosis resulted in prolonged procedures, delayed medical treatments, and ultimately required total femoral replacement with an endoprosthesis.ConclusionIt is important to note that raising awareness of this disease and its potential complications can facilitate timely and appropriate treatment for patients presenting in the early stages of the disease.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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