Cat-scratch disease manifesting as uveitis and binocular fundus nodular lesions: a case report

BMC Ophthalmology

Case Report

Hao Hong¹  Qi An¹  Ye Ying¹  Tianxi Li²  Hu Liu²  Kang Liang² 

[1] Department of Ophthalmology, Nanjing hospital, Nanjing University of Traditional Chinese Medicine, Nanjing, China;Department of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, 210029, Nanjing, China;

关键词: Cat-scratch disease;    Bartonella;    Metagenomics next-generation sequencing (mNGS);    Ocular manifestations;    Fundus;   

DOI  :  10.1186/s12886-023-03063-4

 received in 2023-03-31, accepted in 2023-06-27,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundCat-scratch disease typically presents with various ocular manifestations such as uveitis, vitritis, retinitis, retinochoroiditis, and optic neuritis. However, fundus nodular lesions was rarely reported. In our study, we reported a case of Cat-Scratch disease with binocular fundus nodular lesions.Case presentationAn 11-year old male presented with uveitis in the right eye and bilateral fundus nodular lesions after indirect contact with unvaccinated cats. Comprehensive ancillary examinations including wide-angle fundus photography, ultrasonography, fluorescein fundus angiography, optical coherence tomography, and orbital magnetic resonance imaging were performed to elucidate the multidimensional features of the binocular lesions. Metagenomics next-generation sequencing was utilized to confirm the diagnosis of Cat-scratch disease. The patient’s condition showed improvement after a 6-month combination treatment regimen involving systemic administration of doxycycline hyclate and methylprednisolone tablets, as well as local application of mydriatic and corticosteroid eye drops.ConclusionsWe firstly reported a case of Cat-scratch disease presenting simultaneously with uveitis and fundus nodular lesions caused by Bartonella henselae infection in a child. Timely diagnosis and treatment with antibiotics and corticosteroids showed promising outcomes for the prognosis of these ocular disorders.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

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