Severe macular complications in glaucoma: high-resolution multimodal imaging characteristics and review of the literature

BMC Ophthalmology

Research

Hugo Lama¹  Antoine Rousseau¹  Bénédicte Dupas¹  Marc Labetoulle¹  Christine Fardeau²  Jade Vu³  Jean-François Rouland⁴  Guillaume Besombes⁴  Céline Chaumette⁵  Emmanuelle Brasnu⁵  Antoine Labbé⁵  Michel Pâques⁵  Ismaël Chehaibou⁶ 

[1] Department of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris Saclay, 78, rue du Général Leclerc, 94275, Le Kremlin Bicêtre, France;Department of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris Saclay, 78, rue du Général Leclerc, 94275, Le Kremlin Bicêtre, France;Department of Ophthalmology, Pitié Salpétrière Hospital, APHP, Paris, France;Department of Ophthalmology, Assistance Publique - Hôpitaux de Paris - Université Paris Saclay, 78, rue du Général Leclerc, 94275, Le Kremlin Bicêtre, France;Ophtalmopôle Cochin, APHP, Paris, France;Department of Ophthalmology, Hôpital Claude Huriez, CHRU, Lille, France;Department of Ophthalmology, Quinze-Vingts National Eye Hospital, IHU Foresight, Paris, France;Ophtalmopôle Cochin, APHP, Paris, France;

关键词: Adaptive optics;    Glaucoma;    High-resolution imaging;    Macular edema;    Retinoschisis;    Serous retinal detachment;   

DOI  :  10.1186/s12886-023-03068-z

 received in 2022-08-07, accepted in 2023-07-03,  发布年份 2023

来源: Springer

【 摘 要 】

PurposeTo describe imaging characteristics of severe macular complications occurring in glaucoma and discuss available treatments.MethodsRetrospective case series of glaucomatous patients with macular retinoschisis (MR) and/or serous retinal detachment (SRD). Patients underwent a complete ophthalmological examination and multimodal imaging including retinography, SD-OCT, fluorescein and indocyanine green angiography (FA & ICGA) and adaptive optics (AO).ResultsTen eyes (8 patients) were included. Initial BCVA was 1.04 ± 1.12 logMAR and IOP was 24.0 ± 9.3mmHg. All eyes presented with MR while SRD was present in 5 eyes (5 patients), with a central macular thickness of 573 ± 152 μm. FA and ICGA allowed to exclude leakage in all cases. A focal lamina cribrosa defect (LCD) was found in four eyes (4 patients) using OCT, with AO providing en-face visualization of the defect in one eye. Outer retinal hole was present in 3 eyes (3 patients). No visual improvement or resolution of the macular retinoschisis was observed in eyes with medical or surgical IOP control (N = 9). Vitrectomy with internal membrane limiting peeling and gas tamponade was performed in one eye with good visual results.ConclusionsMultimodal high-resolution imaging is essential to diagnose severe macular complications associated with advanced glaucoma.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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