Pre-exposure prophylaxis uptake for high-risk men who have sex with men in China: a multi-city cross-sectional survey

AIDS Research and Therapy

Research

Xue Yang¹  Xinlun Wang²  Meixia Qu²  Wenting Kang²  Lili Cheng²  Tongtong Liu³  Guang Zhang⁴  Houlin Tang⁴ 

[1] Beijing Huilongguan Hospital, 100096, Beijing, China;Chinese Association of STD and AIDS Prevention and Control, 100050, Beijing, China;Chinese Health Education Center, 100011, Beijing, China;National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, 10226, Beijing, China;

关键词: HIV;    Pre-exposure prophylaxis;    Men who have sex with men;   

DOI  :  10.1186/s12981-023-00528-w

 received in 2023-01-03, accepted in 2023-05-25,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundPre-exposure prophylaxis (PrEP) is a proven biomedical strategy to prevent HIV transmission among men who have sex with men (MSM). Despite oral PrEP is safe and effective in MSM, the use of PrEP has been discouraging, especially in high-risk MSM. And there are no relevant studies showing the use of PrEP in high-risk MSM. The purpose of this study was to get the rate of PrEP use and the factors influencing PrEP use among high-risk MSM.MethodsA cross-sectional study was conducted through an electronic questionnaire on the “i guardian Platform”, and “snowballing” method was used to recruit MSM in six cities in China, including Beijing, Shenzhen, Chengdu, Changsha, Jinan and Nanjing in China, from January to April 2021. Univariate and multivariate logistic regression analysis were used to analyze the factors associated with the use of PrEP among high-risk MSM who had heard about PrEP.ResultsAmong the 1865 high-risk MSM who had heard of PrEP, the rates of those who were willing to use PrEP, had knowledge awareness of PrEP, and had used PrEP were 96.7%, 24.7%, and 22.4%, respectively. Multivariate logistic regression analysis of PrEP use in high-risk MSM showed that more PrEP was used by those who were 26 years or older (OR = 1.86, 95%CI 1.17 ~ 2.99), had master degree or above (OR = 2.37, 95% CI 1.21 ~ 4.72), had unstable work (OR = 1.86, 95% CI 1.16 ~ 2.96), had tested five or more HIV times in the past year (OR = 3.09, 95% CI 1.65 ~ 6.04), had consulted PrEP (OR = 22.05, 95% CI 14.87 ~ 33.91) and had PrEP knowledge awareness (OR = 1.90, 95% CI 1.41 ~ 2.55) (P < 0.05).ConclusionsThe rate of PrEP use in high-risk MSM was relatively low. PrEP was used more by high-risk MSM with unstable jobs, higher education, frequent HIV testing, and PrEP counseling. Public education on PrEP for MSM should continue to be enhanced to help them use PrEP in a timely and accurate manner.

【 授权许可】

CC BY   
© The Author(s) 2023