Age, pelvic incidence, facet joint angle and pedicle-facet angle as correlative factors for isthmic spondylolisthesis: a retrospective case control study

BMC Musculoskeletal Disorders

Research

Bohan Wei¹  Qian Kong¹  Shuoqun Niu¹  Jiawen Liao¹  Yuliang Zu²  Tao Shan³ 

[1] Department of Clinical Medicine, Qingdao Medical College, Qingdao University, 266071, Qingdao, Shandong, People’s Republic of China;Department of Radiology, Qilu Hospital of Shandong University (Qingdao), 266035, Qingdao, Shandong, People’s Republic of China;Human Morphology Laboratory, School of Basic Medicine, Qingdao University, 266071, Qingdao, Shandong, People’s Republic of China;

关键词: Facet joint;    Spinopelvic balance;    Pelvic incidence;    Spondylolisthesis;    Computed tomography;   

DOI  :  10.1186/s12891-023-06569-6

 received in 2022-12-22, accepted in 2023-05-24,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundIsthmic spondylolisthesis (IS) is a common clinical disease with a high incidence rate. However, most current researches explain the clear pathogenesis from a single perspective. The aim of our study was to explore the relationships between multiple parameters in patients and find the potential risk factors of this disease.MethodsOur study retrospectively included 115 patients who were diagnosed with isthmic spondylolisthesis and the same number of individuals without spondylolisthesis. The following parameters were measured or collected: age, pelvic incidence (PI), facet joint angle (FJA) and pedicle-facet angle (P-F angle). The radiographic files were imported into Mimics Medical 20.0 and all collected data were analyzed using SPSS, version 26.0, statistical software.ResultsThe age was higher in IS group than in control group. PI was also higher in the IS group (50.99 ± 7.67) than in the control group (43.77 ± 9.30) significantly (P = 0.009). There was significant difference in cranial and average FJA tropism in L3-L4 level (P = 0.002, P = 0.006, respectively) and in L4-L5 level (P < 0.001). P-F angle of L4-L5 level showed significantly larger in IS group than in control group (P = 0.007).The logistic regression analysis showed a larger age, a greater L3-L4 cranial FJA tropism, and a greater L4-L5 cranial FJA tropism were potential predictors of IS, with an OR of 1.07, 1.28, and 1.39 respectively. The thresholds of the predictors were 60 years, 5.67°, and 8.97° according to the ROC curve. The linear regression equation was established: degree of slippage (%) = 0.220*age − 0.327* L3-4 cranial FJA tropism − 0.346* L4-5 average FJA tropism (F = 3.460, P = 0.011, r = 0.659).ConclusionsOur study revealed that isthmic spondylolisthesis may be related to multiple factors rather than a single factor. Age, PI, PJA and P-F angle are potentially associated with spondylolisthesis.

【 授权许可】

CC BY   
© The Author(s) 2023

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