Mild COVID-19 has no detrimental effect on semen quality

Basic and Clinical Andrology

Research Article

Dunja Maria Baston-Buest¹  Alexandra Petra Bielfeld¹  Jan-Steffen Krüssel¹  Philippos Edimiris¹  Sebastian Buest¹  Cornelius Doehmen²  Lisa Müller³  Marcel Andrée³  Ortwin Adams³ 

[1] Department of OB/GYN and REI (UniKiD), Medical Center, University of Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany;Department of OB/GYN and REI (UniKiD), Medical Center, University of Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany;Kinderwunschzentrum Niederrhein, Madrider Str. 6, 41069, Moenchengladbach, Germany;Institute of Virology, University Hospital Duesseldorf, Heinrich Heine University Duesseldorf, Duesseldorf, Germany;

关键词: COVID-19;    Sperm;    SARS-CoV-2;    Ejaculate;    Pandemic;    COVID-19;    Sperme;    SARS-CoV-2;    Éjaculat;    Pandémie;   

DOI  :  10.1186/s12610-023-00190-2

 received in 2022-12-11, accepted in 2023-02-06,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundAs of today, the effect of coronavirus disease 2019 (COVID-19) on male fertility remains unclear. Studies published so far have partly contradictory results, likely due to very small sample sizes and heterogeneous populations.To gain a deeper understanding of the impact of COVID-19 on male fertility, we performed a prospective case–control study, in which we examined the ejaculate of 37 subjects, including 25 subjects in the acute phase of mild COVID-19 and 12 subjects who did not suffer from COVID-19. Determination of semen parameters, severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) qPCR, and infectivity analysis were performed in the acute phase of the disease and in series.ResultsSemen parameter values did not differ significantly between subjects with mild COVID-19 and the control group. The serial examination of semen parameters revealed no significant changes between 4, 18, and 82 days after the onset of symptoms. SARS-CoV-2 RNA or infectious particles could not be detected in any ejaculate.ConclusionMild COVID-19 seems to have no detrimental effect on semen parameter values.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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