Prevalence of anemia and its associated factors among adult asthmatic patients in Northwest Ethiopia

BMC Pulmonary Medicine

Research

Misganaw Asmamaw Mengstie¹  Endeshaw Chekol Abebe¹  Berihun Bantie²  Gizachew Ambaw Kassie³  Tadesse Asmamaw Dejenie⁴  Yenealem Solomon⁵  Natnael Atnafu Gebeyehu⁶  Molalegn Mesele Gesese⁶  Kirubel Dagnaw Tegegne⁷  Natnael Moges⁸  Anteneh Mengist Dessie⁹  Denekew Tenaw Anley⁹  Melkamu Aderajew Zemene⁹  Sefineh Fenta Feleke^1,10  Getachew Asmare Adella^1,11  Mohammed Abdu Seid^1,12 

[1] Department of Biochemistry, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia;Department of Comprehensive Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia;Department of Epidemiology and Biostatistics, School of Public Health, Woliata Sodo University, Sodo, Ethiopia;Department of Medical Biochemistry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia;Department of Medical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia;Department of Midwifery, College of Medicine and Health Science, Wolaita Sodo University, Wolaita, Ethiopia;Department of Nursing, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia;Department of Pediatrics and Child Health Nursing, College of Health sciences, Debre Tabor University, Debre Tabor, Ethiopia;Department of Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia;Department of Public Health, College of Health Sciences, Woldia University, Woldia, Ethiopia;Department of Reproductive Health and Nutrition, School of Public Health, Woliata Sodo University, Sodo, Ethiopia;Unit of Physiology, Department of Biomedical Science, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia;

关键词: Asthma;    Anemia;    Acute exacerbation;    Hemoglobin level;   

DOI  :  10.1186/s12890-023-02501-9

 received in 2023-03-27, accepted in 2023-05-30,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundAsthma is a heterogeneous disease characterized by chronic airway inflammation. The pathophysiologic processes of asthma can disrupt iron homeostasis, resulting in anemia. However, the association between asthma and anemia among adult asthma patients remains limited. Therefore, the main aim of this study was to determine the prevalence and factors associated with anemia among adult asthmatic patients from May to August 2021.MethodsAn institution-based, cross-sectional study was conducted among 291 asthmatic patients in Northwest Ethiopia. A pre-tested structured questionnaire and checklist were used to collect sociodemographic and clinical data. A blood specimen was collected from asthmatic patients for a complete blood count analysis and morphology assessment. The data were entered into the Epi data software and exported to the statistical package for social science version 20 software for analysis. Non-parametric Mann-Whitney U test was used to compare red blood cell parameters among groups with acute and chronic exacerbations. Binary logistic regression models were used to determine the factors associated with anemia. A p-value less than 0.05 was considered statistically significant.ResultThe overall prevalence of anemia in this study was 11% (95% CI: 7.2–14.8%). Acutely exacerbated asthmatic patients had significantly lower median values of red blood cell parameters such as red blood cell count, hemoglobin, and mean cell hemoglobin when compared to chronic exacerbations. In addition, using systemic corticosteroids (AOR = 4.07, 95% CI: 1.126–14.71, p = 0.032) and being hospitalized in the emergency department (AOR = 3.74, 95% CI: 1.26–11.07, p = 0.017) were found to be significantly associated with anemia.ConclusionThis study demonstrated that anemia was predominant in adult asthma patients. Red blood cell number, hemoglobin level, and mean corpuscular hemoglobin were significantly lower in acute asthma exacerbations. Therefore, appropriate intervention strategies should be undertaken to reduce the prevalence of anemia among adult asthma patients to reduce further complications and provide better monitoring of asthma patients.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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