The reliability and validity of the TBI-CareQOL system in four diverse caregiver groups

Journal of Patient-Reported Outcomes

Research

Angela K. Lyden¹  Zhenke Wu²  Sung Won Choi³  Noelle E. Carlozzi⁴  Christopher Graves⁴  Jennifer A. Miner⁴  Srijan Sen⁵  Angelle M. Sander⁶  Jonathan Troost⁷ 

[1] Clinical Trials Support Office, University of Michigan, Ann Arbor, MI, USA;Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA;Michigan Institute for Data Science, University of Michigan, Ann Arbor, MI, USA;Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA;Department of Physical Medicine and Rehabilitation, University of Michigan, North Campus Research Complex, 2800 Plymouth Road, Building NCRC B14, Room G216, 48109-2800, Ann Arbor, MI, USA;Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA;H. Ben Taub Department of Physical Medicine and Rehabilitation, Baylor College of Medicine/Harris Health System, Houston, TX, USA;Brain Injury Research Center, TIRR Memorial Hermann, Houston, TX, USA;Michigan Institute for Data Science, University of Michigan, Ann Arbor, MI, USA;

关键词: Quality of life;    Informal caregivers;    Caregiver burden;    Patient-reported outcome;    Psychometrics;   

DOI  :  10.1186/s41687-023-00602-x

 received in 2023-01-10, accepted in 2023-06-04,  发布年份 2023

来源: Springer

【 摘 要 】

PurposeEstablishing the psychometric reliability and validity of new measures is an ongoing process. More work is needed in to confirm the clinical utility of the TBI-CareQOL measurement development system in both an independent cohort of caregivers of traumatic brain injury (TBI), as well as in additional caregiver groups.MethodsAn independent cohort of caregivers of people with TBI (n = 139), as well as three new diverse caregiver cohorts (n = 19 caregivers of persons with spinal cord injury, n = 21 caregivers for persons with Huntington disease, and n = 30 caregivers for persons with cancer), completed 11 TBI-CareQOL measures (caregiver strain; caregiver-specific anxiety; anxiety; depression; anger; self-efficacy; positive affect and well-being; perceived stress; satisfaction with social roles and activities; fatigue; sleep-related impairment), as well as two additional measures to examine convergent and discriminant validity (PROMIS Global Health; the Caregiver Appraisal Scale).ResultsFindings support the internal consistency reliability (all alphas > 0.70 with the vast majority being > 0.80 across the different cohorts) of the TBI-CareQOL measures. All measures were free of ceiling effects, and the vast majority were also free of floor effects. Convergent validity was supported by moderate to high correlations between the TBI-CareQOL and related measures, while discriminant validity was supported by low correlations between the TBI-CareQOL measures and unrelated constructs.ConclusionFindings indicate that the TBI-CareQOL measures have clinical utility in caregivers of people with TBI, as well as in other caregiver groups. As such, these measures should be considered as important outcome measures for clinical trials aiming to improve caregiver outcomes.

【 授权许可】

CC BY   
© The Author(s) 2023