Intra-prostatic gold fiducial marker insertion for image-guided radiotherapy (IGRT): five-year experience on 795 patients

BMC Medical Imaging

Research

Bahram Mofid¹  Ali Mahdavi²  Farzad Taghizadeh-Hesary³ 

[1] Department of Radiation Oncology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, 1985717443, Tehran, Iran;Department of Radiology, Imam Hossein Educational Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran;ENT and Head and Neck Research Center and Department, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran;Department of Radiation Oncology, Iran University of Medical Sciences, Tehran, Iran;

关键词: Adverse effects;    Efficacy;    Gold fiducial marker;    Image-guided radiotherapy;    Prostate cancer;   

DOI  :  10.1186/s12880-023-01036-z

 received in 2023-03-22, accepted in 2023-05-29,  发布年份 2023

来源: Springer

【 摘 要 】

IntroductionProstate cancer is the second most commonly diagnosed cancer in males. The use of intra-prostatic fiducial markers (FM) for image-guided radiotherapy (IGRT) has become widespread due to their accuracy, relatively safe use, low cost, and reproducibility. FM provides a tool to monitor prostate position and volume changes. Many studies reported low to moderate rates of complications following FM implantation. In the current study, we present our five years’ experience regarding the insertion technique, technical success, and rates of complication and migration of intraprostatic insertion of FM gold marker.MethodsFrom January 2018 to January 2023, 795 patients with prostate cancer candidate for IGRT (with or without a history of radical prostatectomy) enrolled in this study. We used three fiducial markers (3*0.6 mm) inserted through an 18-gauge Chiba needle under transrectal ultrasonography (TRUS) guidance. The patients were observed for complications up to seven days after the procedure. Besides, the rate of marker migration was recorded.ResultsAll procedures were completed successfully, and all patients tolerated the procedure well with minimal discomfort. The rate of sepsis after the procedure was 1%, and transient urinary obstruction was 1.6%. Only two patients experienced marker migration shortly after insertion, and no fiducial migration was reported throughout radiotherapy. No other major complication was recorded.DiscussionTRUS-guided intraprostatic FM implantation is technically feasible, safe, and well-tolerated in most patients. The FM migration can seldom occur, with negligible effects. This study can provide convincing evidence that TRUS-guided intra-prostatic FM insertion is an appropriate choice for IGRT.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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