The treatment of obesity in children and adolescents: consensus position statement of the Italian society of pediatric endocrinology and diabetology, Italian Society of Pediatrics and Italian Society of Pediatric Surgery

Italian Journal of Pediatrics

Review

Antonino Crinò¹  Elvira Verduci²  Stefano Stagi³  Malgorzata Wasniewska⁴  Domenico Corica⁴  Procolo Di Bonito⁵  Lorenzo Iughetti⁶  Barbara Predieri⁶  Maria Elisabeth Street⁷  Giuliana Valerio⁸  Maria Rosaria Licenziati⁹  Gloria Pelizzo^1,10  Francesca Destro^1,10  Paola Peverelli^1,11  Valeria Calcaterra^1,12  Maria Felicia Faienza^1,13  Luisa deSanctis^1,14  Alice Maguolo^1,15  Claudio Maffeis^1,15  Elena Fornari^1,15  Valentina Mancioppi^1,15  Anita Morandi^1,15  Francesca Olivieri^1,15  Enza Mozzillo^1,16  Adriana Franzese^1,16  Annamaria Staiano^1,16  Mariacarolina Salerno^1,16  Giuseppina Rosaria Umano^1,17  Dario Iafusco^1,17  Emanuele Miraglia Del Giudice^1,17  Anna Di Sessa^1,17  Graziano Grugni^1,18  Ivana Rabbone^1,19  Gianluca Tornese^2,20  Riccardo Lera^2,21  Rita Tanas^2,22  Lia Franca Giusti^2,23  Raffaele Limauro^2,24  Sergio Bernasconi^2,25  Francesca Franco^2,26  Raffaele Buganza^2,27  Salvo Purromuto^2,28  Grazia Filannino^2,29  Nicola Corciulo^3,30  Roberto Franceschi^3,31  Mario Di Pietro^3,32  Danilo Fintini^3,33  Melania Manco^3,34  Beatrice Moro^3,35 

[1] Autoimmune Endocrine Diseases Unit, Bambino Gesù Children Hospital, IRCCS, Rome, Italy;Deparment of Pediatrics, Department of Health Science, Vittore Buzzi Children’s Hospital, University of Milan, Milan, Italy;Department of Health Sciences, University of Florence, Meyer Children’s Hospital IRCCS, Florence, Italy;Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy;Department of Internal Medicine, S. Maria Delle Grazie Hospital, Naples, Pozzuoli, Italy;Department of Medical and Surgical Sciences of Mother, Children and Adults, Pediatric Unit, University of Modena and Reggio Emilia, Modena, Italy;Department of Medicine and Surgery, Unit of Paediatrics, University of Parma, University Hospital of Parma, Parma, Italy;Department of Movement Sciences and Wellbeing, Parthenope University of Naples, Naples, Italy;Department of Neurosciences, Neuro-Endocrine Diseases and Obesity Unit, Santobono-Pausilipon Children’s Hospital, Naples, Italy;Department of Pediatric Surgery, Vittore Buzzi Children’s Hospital, Milan, Italy;Department of Pediatrics and Gynecology, Hospital of Belluno, Belluno, Italy;Department of Pediatrics, Vittore Buzzi Children’s Hospital, Milan, Italy;Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy;Department of Precision and Regenerative Medicine and Ionan Area, University of Bari, Bari, Italy;Department of Sciences of Public Health and Pediatrics, University of Turin, Turin, Italy;Department of Surgery, Dentistry, Pediatrics and Gynecology, Section of Pediatric Diabetes and Metabolism, University of Verona, Verona, Italy;Department of Traslational Medical Sciences, Section of Pediatrics, University of Naples Federico II, Naples, Italy;Department of Woman, Child and General and Specialized Surgery, University of Campania L. Vanvitelli, Naples, Italy;Division of Auxology, Istituto Auxologico Italiano, IRCCS, Verbania, Italy;Division of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy;Institute for Maternal and Child Health, IRCCS “Burlo Garofolo”, Trieste, Italy;Italian Society for Pediatric Endocrinology and Diabetology (SIEDP), Alessandria, Italy;Italian Society for Pediatric Endocrinology and Diabetology (SIEDP), Ferrara, Italy;Italian Society for Pediatric Endocrinology and Diabetology (SIEDP), Lucca, Italy;Local Health Unit Napoli, 3 Sud, Naples, Italy;Microbiome Reaserch Hub, University of Parma, Parma, Italy;Pediatric Department, Azienda Sanitaria Universitaria del Friuli Centrale, Hospital of Udine, Udine, Italy;Pediatric Endocrinology Unit, Department of Public Health and Pediatric Sciences, University of Turin, Turin, Italy;Pediatric Obesity Unit, ASP of Ragusa, Ragusa, Italy;Pediatric Unit Ostuni Hospital, Brindisi, Italy;Pediatric Unit, Hospital of Gallipoli, Lecce, Italy;Pediatric Unit, S. Chiara Hospital, APSS Trento, Trento, Italy;Pediatric and Neonatal Unit, Hospital of Teramo and Atri, Teramo, Italy;Refernce Center for Prader Willi Syndrome, Endocrinology and Diabetology Unit, Bambino Gesù Children Hospital, IRCCS, Rome, Italy;Research Area for Multifactorial Diseases, Children’s Hospital Bambino Gesù, Rome, Italy;UOSD Diabetology, Complesso Ai Colli, AULSS 6 Euganea, Padua, Italy;

关键词: Children;    Adolescents;    Obesity;    Treatment;    Nutrition;    Physical activity;    Cognitive and family-based behavior therapy;    Drug;    Bariatric surgery;   

DOI  :  10.1186/s13052-023-01458-z

 received in 2023-02-21, accepted in 2023-04-18,  发布年份 2023

来源: Springer

【 摘 要 】

This Position Statement updates the different components of the therapy of obesity (lifestyle intervention, drugs, and surgery) in children and adolescents, previously reported in the consensus position statement on pediatric obesity of the Italian Society of Pediatric Endocrinology and Diabetology and the Italian Society of Pediatrics. Lifestyle intervention is the first step of treatment. In children older than 12 years, pharmacotherapy is the second step, and bariatric surgery is the third one, in selected cases. Novelties are available in the field of the medical treatment of obesity. In particular, new drugs demonstrated their efficacy and safety and have been approved in adolescents. Moreover, several randomized control trials with other drugs are in process and it is likely that some of them will become available in the future. The increase of the portfolio of treatment options for obesity in children and adolescents is promising for a more effective treatment of this disorder.

【 授权许可】

CC BY   
© The Author(s) 2023