Gauging innovation and health impact from biomedical research: survey results and interviews with recipients of EU-funding in the fields of Alzheimer’s disease, breast cancer and prostate cancer

Health Research Policy and Systems

Review

Christina Kyriakopoulou¹  Christian Desaintes¹  Sergio Di Virgilio¹  Francesca Pistollato²  Ivana Campia²  Camilla Bernasconi²  Pierre Deceuninck²  Evangelos P. Daskalopoulos²  Maurice Whelan² 

[1] European Commission, DG Research & Innovation (DG RTD), Brussels, Belgium;European Commission, Joint Research Centre (JRC), Directorate F-Health, Consumers and Reference Materials, Via E. Fermi 2749, 21027, Ispra, VA, Italy;

关键词: Alzheimer’s disease;    Breast cancer;    Prostate cancer;    Biomedical research;    Impact;    EU funding;    Indicators;    Non-animal models;   

DOI  :  10.1186/s12961-023-00981-z

 received in 2022-10-03, accepted in 2023-04-05,  发布年份 2023

来源: Springer

【 摘 要 】

Biomedical research on Alzheimer’s disease (AD), breast cancer (BC) and prostate cancer (PC) has globally improved our understanding of the etiopathological mechanisms underlying the onset of these diseases, often with the goal to identify associated genetic and environmental risk factors and develop new medicines. However, the prevalence of these diseases and failure rate in drug development remain high. Being able to retrospectively monitor the major scientific breakthroughs and impact of such investment endeavors is important to re-address funding strategies if and when needed. The EU has supported research into those diseases via its successive framework programmes for research, technological development and innovation. The European Commission (EC) has already undertaken several activities to monitor research impact. As an additional contribution, the EC Joint Research Centre (JRC) launched in 2020 a survey addressed to former and current participants of EU-funded research projects in the fields of AD, BC and PC, with the aim to understand how EU-funded research has contributed to scientific innovation and societal impact, and how the selection of the experimental models may have underpinned the advances made. Further feedback was also gathered through in-depth interviews with some selected survey participants representative of the diverse pre-clinical models used in the EU-funded projects. A comprehensive analysis of survey replies, complemented with the information derived from the interviews, has recently been published in a Synopsis report. Here we discuss the main findings of this analysis and propose a set of priority actions that could be considered to help improving the translation of scientific innovation of biomedical research into societal impact.

【 授权许可】

CC BY   
© European Union 2023

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