Uveitis including Vogt-Koyanagi-Harada syndrome following inactive covid-19 vaccination: a case series

Journal of Ophthalmic Inflammation and Infection

Research

Mohamad-Reza Ansari-Astaneh¹  Mehrdad Motamed Shariati¹  Mojtaba Abrishami¹  Shahin Jahani¹  Ali Bolouki¹  Seyedeh Maryam Hosseini¹ 

[1]Eye Research Center, Mashhad University of Medical Sciences, Khatam Al-Anbia Eye Hospital, Qarani Blvd, 9195965919, Mashhad, Iran

关键词: Coronavirus disease 2019;    COVID-19 vaccination;    Severe acute respiratory syndrome coronavirus 2;    Sinopharm vaccine;    Uveitis;    Vogt-Koyanagi-Harada;   

DOI  :  10.1186/s12348-023-00347-0

 received in 2022-02-24, accepted in 2023-04-30,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundCurrently, large populations have been vaccinated against COVID-19. The whole inactivated Sinopharm COVID-19 vaccine has been the main available COVID-19 vaccine in Iran. Ocular inflammatory reactions have been reported following vaccination. The present case reports aim to introduce four cases of uveitis after the Sinopharm vaccine administration.Case presentationOur first reported case is a 38-year-old woman with a positive medical history of inactive ulcerative colitis. Active uveitis had developed following the second dose of the COVID-19 vaccination. The remaining three cases were healthy individuals who developed the first episode of uveitis, after the COVID-19 vaccine administration. Vogt-Koyanagi-Harada syndrome was the final diagnosis in one of the aforementioned cases. All four patients demonstrated favorable responses to corticosteroid treatment.ConclusionThese observations are in line with incoming reports from all around the world and raise concerns about the possibility of post-vaccination uveitis development, especially in cases with a previous history of auto-immune systemic diseases or inactive uveitis.

【 授权许可】

CC BY   
© The Author(s) 2023

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