Undernutrition and 60-day mortality in critically ill children with respiratory failure: a prospective cohort study

BMC Pediatrics

Research

Yasaman Dadashi-noshahr¹  Sina Amirjani¹  Zahra Vahdat Shariatpanahi²  Narjes Ahmadizadeh³  Azita Behzad³ 

[1] Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran;Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran;PO Box: 19395-4741, Address: Farahzadi Blvd., Shahrak Qods, 1981619573, Baran, Tehran, West Arghavan, Iran;Department of Critical care, Mofid children’s hospital, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran;

关键词: Nutritional status;    Mortality;    Underfeeding;    PIM2;   

DOI  :  10.1186/s12887-023-04087-x

 received in 2023-02-02, accepted in 2023-05-23,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundTo determine whether undernutrition affects 60-day mortality in pediatric acute respiratory failure.MethodsSubjects with acute respiratory failure aged between two months and 13 years were included in the study. The Z-scores were calculated on admission and children were categorized into two groups of undernutrition and normal nutrition. The nutritional intake of the children was measured daily. The outcome was 60-day mortality.ResultsA total of 126 patients met the inclusion criteria; 41% were undernourished based on the Z-score of BMI and weight for height, 50% based on the Z-score of height and length for age and 45% based on the Z-score of weight for age. Overall, the 60-day mortality rate was 27.8%. The Cox regression analysis adjusted with PIM2, age and gender, showed that undernutrition has a significant relationship with 60-day mortality based on the weight for age Z-score (HR = 2.33; CI: 1.175–4.638). In addition, undernutrition has a significant relationship with 60-day mortality based on the BMI for age (HR = 3.04; CI:1.070–8.639) and weight for height (HR = 2.62; CI: 1.605–6.658) Z-scores. The mean calorie and protein intake of 72% of the children was less than 80% of their calorie needs. The time to start feeding in 63% of the children was more than 48 h. There was no relationship between the time of starting nutrition and nutritional intake during PICU admission and mortality.ConclusionUndernutrition is prevalent in mechanically ventilated children in the PICU and may be associated with 60-day mortality.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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