Trend analysis of hepatitis B and C among patients visiting health facility of Tigrai, Ethiopia, 2014–2019

BMC Gastroenterology

Research

Brhane Berhe¹  Aderajew Gebrewahd¹  Fitsum Mardu¹  Hadush Negash¹  Haftom Legese¹  Guesh Gebremariam¹  Tsega Kahsay¹  Gebre Adhanom¹  Kebede Tesfay¹  Haftay Gebremedhin² 

[1] Department of Medical Laboratory, College of Health Sciences, Adigrat University, Adigrat City, Tigrai, Ethiopia;Department of Public Health, College of Health Sciences, Adigrat University, Adigrat City, Tigrai, Ethiopia;

关键词: Ethiopia;    Hepatitis B;    Hepatitis C virus;    Tigrai;    Trend;   

DOI  :  10.1186/s12876-023-02807-2

 received in 2023-03-02, accepted in 2023-05-09,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundHepatitis B and C viruses are the major public health concerns of the globe. The two hepatotropic viruses share common modes of transmission and their co-infection is common. Despite the provision of an effective prevention mechanism, the infections caused by these viruses remain a significant problem worldwide, particularly among developing countries like Ethiopia.MethodsThis institutional-based retrospective study was conducted between January 2014 December and December 2019 from documented laboratory logbooks of Adigrat general hospital serology laboratory, Tigrai, Ethiopia. data were collected and checked for completeness on a daily based, coded, entered, and cleaned using Epinfo version 7.1, exported and analyzed using SPSS version 23. Binary logistic regression analysis and Chi-square test (X2) assessed the association between dependent and independent variables. The corresponding variables with a P-value (P < 0.05) and 95% confidence interval were considered statistically significant.ResultsOut of 20,935 clinically suspected individuals, 20,622 were given specimens and tested for hepatitis B and C viruses with total completeness of 98.5%. The overall prevalence of hepatitis B and hepatitis C virus was found to be 3.57% (689/19,273) and 2.13% (30/1,405), respectively. The positivity rate of the hepatitis B virus was 8.0% (106/1317) and 3.24% (583/17,956) among males and females, respectively. Additionally, 2.49%( 12/481) of males and 1.94% (18/924) of females were positive for hepatitis C virus infection. The overall prevalence of co-infection for both hepatitis B and hepatitis C virus was 7.4% (4/54). Sex and age were significantly associated with hepatitis B and C virus infection.ConclusionsThe overall prevalence of hepatitis B and C is low intermediate according to the WHO criteria. Although there was a fluctuating trend of hepatitis B and C through the years 2014–2019, the result shows moreover declining trend. Both hepatitis B and C share similar routes of transmission and affect all age categories but males were more highly affected than females. Therefore, awareness creation of the community about the methods of transmission, education about prevention, and control of hepatitis B and C virus infection, and improving coverage of youth-friendly services in health facilities should be strengthened.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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