Malaria prevalence in Mauritania: a systematic review and meta-analysis

Malaria Journal

Research

Sébastien Briolant¹  Leonardo Basco²  Inejih El Moustapha³  Khyarhoum Brahim³  Mohamed Ouldabdallahi Moukah³  Mohamed Salem Ould Ahmedou Salem³  Ali Ould Mohamed Salem Boukhary⁴ 

[1] Aix Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France;IHU-Méditerranée Infection, Marseille, France;Unité de Parasitologie Entomologie, Département de Microbiologie et Maladies Infectieuses, Institut de Recherche Biomédicale des Armées (IRBA), Marseille, France;IHU-Méditerranée Infection, Marseille, France;Unité de Parasitologie Entomologie, Département de Microbiologie et Maladies Infectieuses, Institut de Recherche Biomédicale des Armées (IRBA), Marseille, France;Université de Nouakchott, UR-GEMI, nouveau campus universitaire, BP 5026, Nouakchott, Mauritania;Université de Nouakchott, UR-GEMI, nouveau campus universitaire, BP 5026, Nouakchott, Mauritania;Aix Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France;

关键词: Malaria;    Meta-analysis;    Mauritania;    Prevalence;    Plasmodium falciparum;    Plasmodium vivax;    Systematic review;   

DOI  :  10.1186/s12936-023-04569-4

 received in 2023-02-24, accepted in 2023-04-20,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundUnderstanding malaria epidemiology is a critical step toward efficient malaria control and elimination. The objective of this meta-analysis was to derive robust estimates of malaria prevalence and Plasmodium species from studies conducted in Mauritania and published since 2000.MethodsThe present review followed the PRISMA guidelines. Searches were conducted in various electronic databases such as PubMed, Web of Science, and Scopus. To obtain pooled prevalence of malaria, meta-analysis was performed using the DerSimonian-Laird random-effects model. Methodological quality of eligible prevalence studies was assessed using Joanna Briggs Institute tool. Inconsistency and heterogeneity between studies were quantified by the I2 index and Cochran’s Q test. Publication bias was assessed with funnel plots and Egger’s regression tests.ResultsA total of 16 studies with a good individual methodological quality were included and analysed in this study. The overall random effects pooled prevalence of malaria infection (symptomatic and asymptomatic) across all included studies was 14.9% (95% confidence interval [95% CI]: 6.64, 25.80, I2 = 99.8%, P < 0.0001) by microscopy, 25.6% (95% CI: 8.74, 47.62, I2 = 99.6%, P < 0.0001) by PCR and 24.3% (95% CI: 12.05 to 39.14, I2 = 99.7%, P < 0.0001) by rapid diagnostic test. Using microscopy, the prevalence of asymptomatic malaria was 1.0% (95% CI: 0.00, 3.48) against 21.46% (95% CI: 11.03, 34.21) in symptomatic malaria. The overall prevalence of Plasmodium falciparum and Plasmodium vivax was 51.14% and 37.55%, respectively. Subgroup analysis showed significant variation (P = 0.039) in the prevalence of malaria between asymptomatic and symptomatic cases.ConclusionPlasmodium falciparum and P. vivax are widespread in Mauritania. Results of this meta-analysis implies that distinct intervention measures including accurate parasite-based diagnosis and appropriate treatment of confirmed malaria cases are critical for a successful malaria control and elimination programme in Mauritania.

【 授权许可】

CC BY   
© The Author(s) 2023

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