Pediatric hypereosinophilic syndrome associated with liver damage, portal vein, splenic vein and superior mesenteric vein thromboses: a case report

BMC Pediatrics

Case Report

Shu-Xia Ma¹  Qian-Yi Zhao¹  Hai-Tao Zheng¹  Yong-Bin Yan¹  Ling-Ling Liu¹  Xiao-Yu Yan²  Yan Xu³ 

[1] Department of Pediatrics, The First Affiliated Hospital of Henan University of Chinese Medicine, 19 Renmin Road, 450003, Zhengzhou, Henan, China;Henan University of Chinese Medicine School of Pediatrics, Zhengzhou, China;First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou, China;Henan University of Chinese Medicine, Zhengzhou, China;

关键词: Hypereosinophilic syndrome;    Thrombocytopenia;    Liver damage;    Portal vein;    Splenic vein;    Superior mesenteric vein;    Thrombosis;   

DOI  :  10.1186/s12887-023-04014-0

 received in 2022-11-21, accepted in 2023-04-15,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundThe hypereosinophilic syndrome (HES) is a group of rare blood disorders characterized by persistent eosinophilia and damage to multiple organs. HES can be either primary, secondary or idiopathic. Secondary HES are commonly caused by parasitic infections, allergic reactions or cancer. We described a pediatric case of HES associated with liver damage and multiple thrombi.Case summaryA 12-year-old boy with eosinophilia was complicated with severe thrombocytopenia, liver damage, portal vein, splenic vein, and superior mesenteric vein thromboses. The thrombi recanalized after treatment with methylprednisolone succinate and low molecular weight heparin. No side effects appeared after 1-month.ConclusionsCorticosteroids should be used at an early stage of HES to prevent further damage to vital organs. Anticoagulants should be recommended only in cases with thrombosis which should be actively screened as a part of evaluation of end organ damage.

【 授权许可】

CC BY   
© The Author(s) 2023

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