Postoperative effect of sufentanil preemptive analgesia combined with psychological intervention on breast cancer patients

BMC Anesthesiology

Research

Quan Shi¹  Yihong Jiang¹  Wei Liang¹  Hong Tan¹  Di Li²  Chengqiang Wang² 

[1] Department of Anesthesiology, the Affiliated Hospital of Guilin Medical University, 541001, Guilin, Guangxi, China;Department of Epidemiology and Statistics, School of Public Health, Guilin Medical University, 541199, Guilin, Guangxi, China;

关键词: Sufentanil;    Preoperative analgesia;    Psychological intervention;    Breast cancer patients;   

DOI  :  10.1186/s12871-023-02143-8

 received in 2022-10-25, accepted in 2023-05-16,  发布年份 2023

来源: Springer

【 摘 要 】

ObjectivesTo explore the postoperative effects of sufentanil preemptive analgesia combined with psychological intervention on breast cancer patients undergoing radical surgery.Methods112 female breast cancer patients aged 18–80 years old who underwent radical surgery by the same surgeon were randomly divided into 4 groups, and there were 28 patients in each group. Patients in group A were given 10 µg sufentanil preemptive analgesia combined with perioperative psychological support therapy (PPST), group B had only 10 µg sufentanil preemptive analgesia, group C had only PPST, and group D were under general anesthesia with conventional intubation. Visual analogue scoring (VAS) was used for analgesic evaluation at 2, 12 and 24 h after surgery and compared among the four groups by ANOVA method.ResultsThe awakening time of patients in group A or B was significantly shorter than that in group C or D, and the awakening time in group C was significantly shorter than that in group D. Moreover, patients in group A had the shortest extubation time, while the group D had the longest extubation time. The VAS scores at different time points showed significant difference, and the VAS scores at 12 and 24 h were significantly lower than those at 2 h (P < 0.05). The VAS scores and the changing trend of VAS scores were varied among the four groups (P < 0.05). In addition, we also found that patients in group A had the longest time to use the first pain medication after surgery, while patients in group D had the shortest time. But the adverse reactions among the four groups showed no difference.ConclusionsSufentanil preemptive analgesia combined with psychological intervention can effectively relieve the postoperative pain of breast cancer patients.

【 授权许可】

CC BY   
© The Author(s) 2023

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