Voltammetric investigations of functional dyspepsia drug acotiamide at pencil graphite electrode: An eco-friendly and cost effective stripping detection method

Indian Journal of Chemical Technology

article

Rinky Agarwal¹  Rajesh Yadav¹  Raj Kumar Sharma²  D K Sharma¹  K K Jhankal¹ 

[1] Electrochemical Sensor Research Laboratory, Department of Chemistry, University of Rajasthan Jaipur 302 004;Department of Chemistry, Shri Bhawani Niketan PG College

关键词: Acotiamide;    BR buffer;    Functional dyspepsia;    Pencil graphite electrode;    Stripping voltammetry;    Article;   

DOI  :  10.56042/ijct.v30i1.58991

学科分类：化学（综合）

来源: National Institute of Science Communication and Information Resources

【 摘 要 】

First time, the electro-oxidative behaviour and determination of acotiamide at a pencil graphite electrode have been investigated under different experimental conditions using cyclic voltammetry (CV), differential pulse anodic stripping voltammetry (DPASV), and square wave anodic stripping voltammetric (SWASV) techniques. The voltammetric responses of acotiamide have been analyzed at different scan rates, pH and concentrations. Oxidation of acotiamide at the surface of pencil graphite electrode gave two well defined irreversible peaks in the voltammograms in BR buffer of pH 7.0. The oxidation process is completely diffusion controlled. A linear response of peak current has been obtained between 15.5 to 124 μM in non-aqueous media for all the voltammetric techniques. The proposed DPASV and SWASV techniques show limit of detection at 18.58 and 13.36 μM, respectively.

【 授权许可】

CC BY-NC-ND