Granulocyte and monocyte/macrophage apheresis for the treatment of immune-mediated inflammatory arthropathies: case reports

Drugs in Context

article

Ana Victoria Carro Martínez¹  Lydia Montolio Chiva¹  Montserrat Robustillo Villarino¹ 

[1] Rheumatology Unit, Hospital Universitario de La Plana

关键词: disease-modifying anti-rheumatic drugs;    leukapheresis;    non-steroidal anti-inflammatory agents;    pain;    psoriatic arthritis;    rheumatoid arthritis;   

DOI  :  10.7573/dic.2021-8-5

学科分类：社会科学、人文和艺术（综合）

来源: C S F Medical Communications Ltd.

【 摘 要 】

Drug therapy of immune-mediated inflammatory arthropathies is not always satisfactory, and there is a risk of adverse events. Granulocyte and monocyte/macrophage apheresis (GMA) is a non-pharmacological therapeutic option that is beneficial and very well tolerated. GMA involves passing blood through a column with cellulose acetate beads to remove increased and activated myeloid lineage cells and improve the cytokine profile. The technique reduces pain and inflammation. We present four clinical reports that illustrate the clinical uses of GMA with the medical device Adacolumn® in patients with different backgrounds and immune-mediated inflammatory arthritis. The results were positive, and no adverse events were reported.

【 授权许可】

CC BY-NC-ND