A formalization of one of the main claims of “TDP-43 represses cryptic exon inclusion in FTD/ALS gene UNC13A” by Rosa Ma et al. 2021

Data Science

article

Matthew Brauer¹ 

[1] Maze Therapeutics

关键词: UNC13A;    TAR DNA binding protein;    inclusion of cryptic exon;   

DOI  :  10.3233/DS-210046

来源: IOS Press

【 摘 要 】

Rosa Ma et al. claimed in previous work that the protein TDP-43 represses cryptic exon inclusion in the gene UNC13A. We present here a formalization of that claim, stating that all things of class “TAR DNA binding protein” that are in the context of a thing of class “UNC13A” generally have a relation of type “inhibits” to a thing of class “inclusion of cryptic exon” in the same context.

【 授权许可】

Unknown