A Comment on Sample Size Calculation for Analysis of Covariance in Parallel Arm Studies

Journal of Biometrics & Biostatistics

article

Guogen Shan¹  Changxing Ma² 

[1] Epidemiology and Biostatistics Program, Department of Environmental and Occupational Health, School of Community Health Sciences, University of Nevada Las Vegas;Department of Biostatistics, University at Buffalo

关键词: Analysis of covariance;    F distribution;    Sample size;    Power;   

DOI  :  10.4172/2155-6180.1000184

来源: Hilaris Publisher

【 摘 要 】

We compare two sample size calculation approaches for analysis of covariance with one covariate. Exact simulation studies are conducted to compare the sample size calculation based on an approach by Borm et al. (2007) (referred to as the B approach) and an exact approach (referred to as the F approach). Although the B approach and the F approach have similar performance when the correlation coefficient is small, the F approach generally has a more accurate sample size calculation as compared to the B approach. Therefore, the F approach for sample size calculation is generally recommended for use in practice.

【 授权许可】

Unknown