Maximising impactful, locally relevant global mental health research conducted in low and middle income country settings: ethical considerations

Wellcome Open Research

article

Clara Calia¹  Amit Chakrabarti²  Emmanuel Sarabwe³  Anna Chiumento⁴ 

[1] Clinical Psychology, University of Edinburgh;ICMR-Centre for Ageing and Mental Health, Division of Non-Communicable Diseases, Indian Council of Medical Research;Quality Assurance, Community Based Sociotherapy;Primary Care and Mental Health, University of Liverpool

关键词: Global Mental Health;    Bioethics;    Research ethics;    Low and middle income countries;    Community engagement;    Impact;    International partnerships;   

DOI  :  10.12688/wellcomeopenres.18269.2

学科分类：内科医学

来源: Wellcome

【 摘 要 】

Background: Achieving ethical and meaningful mental health research in diverse global settings requires approaches to research design, conduct, and dissemination that prioritise a contextualised approach to impact and local relevance.Method: Through three case studies presented at the 2021 Global Forum on Bioethics in Research meeting on the ethical issues arising in research with people with mental health conditions, we consider the nuances to achieving ethical and meaningful mental health research in three diverse settings. The case studies include research with refugees Rwanda and Uganda; a neurodevelopmental cohort study in a low resource setting in India, and research with Syrian refugees displaced across the Middle East.Results: Key considerations highlighted across the case studies include how mental health is understood and experienced in diverse contexts to ensure respectful engagement with communities, and to inform the selection of contextually-appropriate and feasible research methods and tools to achieve meaningful data collection.  Related to this is a need to consider how communities understand and engage with research to avoid therapeutic misconception, exacerbating stigma, or creating undue inducement for research participation, whilst also ensuring meaningful benefit for research participation. Central to achieving these is the meaningful integration of the views and perspectives of local stakeholders to inform research design, conduct, and legacy. The case studies foreground the potential tensions between meeting local community needs through the implementation of an intervention, and attaining standards of scientific rigor in research design and methods; and between adherence to procedural ethical requirements such as ethical review and documenting informed consent, and ethical practice through attention to the needs of the local research team.Conclusions: We conclude that engagement with how to achieve local relevance and social, practice, and academic impact offer productive ways for researchers to promote ethical research that prioritises values of solidarity, inclusion, and mutual respect.

【 授权许可】

CC BY