Malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the Saraya health district, southern Senegal

Wellcome Open Research

article

Isaac Akhenaton Manga¹  Mamadou Sarifou BA¹  Fassiatou Tairou¹  Amadou Seck¹  Ekoue Kouevidjin¹  Doudou Sow¹  Khadime Sylla¹  Magatte Ndiaye¹  Fatou Ba Fall³  Alioune Babara Gueye³  Ibrahima Diallo³  Médoune Ndiop³  Mady Ba³  Roger Clément Tine¹  Omar Gaye¹  Babacar Faye¹  Jean Louis Abdourahim Ndiaye¹ 

[1] Parasitology-Mycology Department, Faculty of Medicine, Pharmacy and Ondontology, Cheikh Anta Diop University of Dakar;Ministry of Health and Social Action;National Malaria Control Program;Service of Parasitology Mycology, Department of Medical Biology, UFR Santé/University Iba Der Thiam

关键词: seasonal malaria chemoprevention;    Plasmodium;    carriage;    Senegal;    malaria;   

DOI  :  10.12688/wellcomeopenres.17888.2

学科分类：内科医学

来源: Wellcome

【 摘 要 】

Background: Seasonal malaria chemoprevention (SMC) has been adopted and implemented in the southern regions of Senegal in children aged between three and 120 months since 2013. Scaling up this strategy requires its evaluation to assess the impact. This study was carried out to determine the dynamics ofPlasmodium falciparum carriage before and after two years of SMC implementation.Methods: Four household surveys were conducted in villages in the health district of Saraya, which is a SMC implementation area in Senegal. These villages were selected using probability proportional to size sampling. Each selected village was divided into segments containing at least 50 children. In each segment, a household questionnaire was administered to the parents or legal representatives of children aged three to 120 months. Blood smears were collected to determineP. falciparum prevalence by microscopy one month before the first round of SMC, one month after the last round of the first SMC campaign and two years after the start of the implementation.Results: A total of 2008 children were included with a mean average age of 4.81 (+/-2.73) years. Of the study population, 50.33% were more than five years old and 50.3% were male. In 2013, mosquito net ownership was 99.4 % before the SMC campaign and 97.4% after. In 2015, it was 36.6% before and 45.8% after the campaign. In 2013, the prevalence of plasmodium carriage was 11.8% before and 6.1% after the SMC campaign. In 2015, the prevalence was 4.9% before the administration of SMC and this increased up to 15.3% after. Malaria prevalence was high among children over five years old and in boys.Conclusions: The decrease inPlasmodium falciparum parasite prevalence, which subsequently increased after two years of SMC implementation in this study, suggests adding an extra cycle of the SMC or adjusting the administration period.

【 授权许可】

CC BY