The Avon Longitudinal Study of Parents and Children - A resource for COVID-19 research: Generation 2 questionnaire data capture May-July 2020

Wellcome Open Research

article

Daniel Smith¹  Kate Northstone¹  Claire Bowring¹  Nicholas Wells¹  Michael Crawford¹  Rebecca M. Pearson²  Amy Thomas⁵  Ellen Brooks-Pollock¹  Deborah A. Lawlor²  Nicholas John Timpson¹ 

[1] ALSPAC, Department of Population Health Sciences, Bristol Medical School, University of Bristol;MRC Integrative Epidemiology Unit, University of Bristol;Population Health Sciences, Bristol Medical School, University of Bristol;NIHR Bristol Biomedical Research Centre;Bristol Veterinary School, University of Bristol

关键词: ALSPAC;    Children of the 90s;    Cross-generation;    COVID-19;    Coronavirus;    Children;    Mental Health;    Contact Patterns;   

DOI  :  10.12688/wellcomeopenres.16414.2

学科分类：内科医学

来源: Wellcome

【 摘 要 】

The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective population-based cohort study which recruited pregnant women in 1990-1992 from the Bristol area (UK). ALSPAC has followed these women, their partners (Generation 0; G0) and their offspring (Generation 1; G1) ever since. From 2012, ALSPAC has identified G1 participants who were pregnant (or their partner was) or had become parents, and enrolled them, their partners, and children in the ALSPAC-Generation 2 (ALSPAC-G2) study, providing a unique multi-generational cohort. At present, approximately 1,100 G2 children (excluding thosein utero) from 810 G1 participants have been enrolled. In response to the COVID-19 pandemic, ALSPAC rapidly deployed two online questionnaires; one during the initial lockdown phase in 2020 (9th April-15th May), and another when national lockdown restrictions were eased (26th May-5th July). As part of this second questionnaire, G1 parents completed a questionnaire about each of their G2 children. This covered: parental reports of children’s feelings and behaviour since lockdown, school attendance, contact patterns, and health. A total of 289 G1 participants completed this questionnaire on behalf of 411 G2 children. This COVID-19 G2 questionnaire data can be combined with pre-pandemic ALSPAC-G2 data, plus ALSPAC-G1 and -G0 data, to understand how children’s health and behaviour has been affected by the pandemic and its management. Data from this questionnaire will be complemented with linkage to health records and results of biological testing as they become available. Prospective studies are necessary to understand the impact of this pandemic on children’s health and development, yet few relevant studies exist; this resource will aid these efforts. Data has been released as: 1) a freely-available dataset containing participant responses with key sociodemographic variables; and 2) an ALSPAC-held dataset which can be combined with existing ALSPAC data, enabling bespoke research across all areas supported by the study.

【 授权许可】

CC BY