NeuroChaT: A toolbox to analyse the dynamics of neuronal encoding in freely-behaving rodents in vivo

Wellcome Open Research

article

Nurul Islam¹  Seán K. Martin¹  John P. Aggleton²  Shane M. O’Mara¹ 

[1] Institute of Neuroscience, Trinity College Dublin;School of Psychology, Cardiff University

关键词: Cognitive map;    data analysis;    spatial coding;    single unit;    open software;    electrophysiology;   

DOI  :  10.12688/wellcomeopenres.15533.1

学科分类：内科医学

来源: Wellcome

【 摘 要 】

There is a dearth of freely-available, standardised open source analysis tools available for the analysis of neuronal signals recordedin vivo in the freely-behaving animal. In response, we have developed a freely-available, open-source toolbox, NeuroChaT (NeuronCharacterisationToolbox), specifically addressing this lacuna. Although we have particularly emphasised single unit analyses for spatial coding, NeuroChaT also characterises rhythmic properties of units and their dynamics associated with local field potential signals. NeuroChaT was developed using Python and facilitates a complete pipeline from automation of analysis to producing and managing publication-quality figures. Additionally, we have adopted a platform-independent format (Hierarchical Data Format version 5) for storing recorded and analysed data. By providing an easy-to-use software package, we aim to simplify the adoption of standardised analyses for behavioural neurophysiology and facilitate open data sharing and collaboration between laboratories.

【 授权许可】

CC BY