Molecular modeling and screening of antiviral peptides for Influenza A virus polymerase basic protein 2(PB2) protein using Hpepdock software for the therapy of Influenza A

Cardiometry

article

Anusha G¹  Monisha M¹ 

[1] Department of Biomedical Engineering, Saveetha School of Engineering, Saveetha University

关键词: Antiviral peptides;    Influenza A virus;    Novel Peptide;    Molecular docking;    PB2 protein;    Hpepdock;    PEPstrMOD;   

DOI  :  10.18137/cardiometry.2022.25.16931701

学科分类：环境科学（综合）

来源: Russian New University

【 摘 要 】

0.05 insignificant (-202.728Kcal/mol), p=0.001, p0.05 insignificant (-195,788 Kcal/mol) showed better results in comparison to reference Macrocyclic iHA-100 peptide (-154.392 Kcal/mol). Conclusion: The identified antiviral peptides could more effectively inhibit PB2 protein than the other available peptides on the market to treat Influenza A viral disease.

【 授权许可】

CC BY