Polycyclic Aromatic Hydrocarbons and Their Effects on the Occurrence of Chronic Obstructive Pulmonary Disease (COPD): A Review

Jundishapur Journal of Chronic Disease Care

article

Mohammad Javad Mohammadi¹  GholamrezaGoudarzi²  Behzad Fouladi Dehaghi³  Kourosh Zarea⁴  Maryam Hormati⁵  Masoume Taherian⁵  Fatemeh Kiani⁵ 

[1] Department of Environmental Health Engineering, School of Public Health and Environmental Technologies Research Center, Ahvaz Jundishapur University of Medical Sciences;Department of Environmental Health Engineering, School of Public Health and Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences;Department of Occupational Health, School of Health, Environmental Technology Research Center, Ahvaz Jundishapur University of Medical Sciences;Nursing Care Research Center in Chronic Diseases, Department of Nursing, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences;Student Research Committee, Ahvaz Jundishapur University of Medical Sciences

关键词: Polycyclic Aromatic Hydrocarbons;    Health Effect;    Chronic Obstructive Pulmonary;    Cancer;   

DOI  :  10.5812/jjcdc-122852

来源: Kowsarmedical

【 摘 要 】

Background: Polycyclic aromatic hydrocarbons (PAHs) are among the most important compounds that cause adverse health outcomes in humans, such as poor lung function, bronchitis, asthma, shortness of breath, circulatory disorders, lung cancer, cardiovascular diseases, and mortality. Objectives: This review aims to investigate the effects of PAHs on the occurrence of chronic obstructive pulmonary disease (COPD). Methods: A narrative review of the literature was done from 1979 to 2021 in various databases: Science Direct, PubMed, Web of Science, Springer, and Google Scholar. We found 76 and 14 articles by searching the databases and other sources, respectively. Twelve articles were included after screening. The literature indicates the significant adverse effect of PAHs on the occurrence of COPD. Results: Heavy industries (oil, steel, gas, and petroleum) are the primary sources of PAHs. Polycyclic aromatic hydrocarbons induce respiratory diseases, as they are destructive to the lung, leading to COPD. Sex, age, nutritional status, health, duration of exposure to PAHs, and body response to the pollutants affect the complications. Conclusions: High PAH levels can increase the risk of COPD, respiratory diseases, and incremental lifetime cancer risk (ILCR).

【 授权许可】

Unknown