Wet cupping therapy increases the time withdrawal latency (TWL) and decreases GABA-A receptor expression in the spinal cord in a rat model of neuropathic pain

Anaesthesia, Pain & Intensive Care

article

Hanik Badriyah Hidayati¹  Ema Qurnianingsih³  Widjiati .⁴  Siti Khaerunnisa³  Vania Ayu Puspamaniar⁵  Rizky Danang Susetyo⁶ 

[1] Department of Neurology, Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital;Moestopo Street;Physiology and Medical Biochemistry Department, Faculty of Medicine Airlangga University;Faculty of Veterinary Medicine, Airlangga University;Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital;Faculty of Science and Technology, Airlangga University

关键词: Chronic constriction injury;    CCI rat model;    GABA-A receptors;    Neuropathic pain;    Pain;    Time withdrawal latency;    TWL;    Wet cupping therapy;   

DOI  :  10.35975/apic.v27i1.2124

学科分类：社会科学、人文和艺术（综合）

来源: THK

【 摘 要 】

Background & Objective: Neuropathic pain (NP) is a pain due to a somatosensory lesion. NP leads to disruption of health, work, social relationships, hobbies, sleep, mood, and cognitive function. Up till now, the treatment of NP remains unsatisfactory. It makes many patients seek alternative therapies, including wet cupping therapy (WCT). We aimed to analyze the effects of WCT against NP in chronic constriction injury (CCI) in a rat model by assessing the increase in time withdrawal latency (TWL) and GABA-A receptors expression in the spinal cord.

【 授权许可】

CC BY-NC