Intrathecal bupivacaine-fentanyl and bupivacaine-dexmedetomidine for cesarean section: a randomized controlled trial

Anaesthesia, Pain & Intensive Care

article

Sana Urooj¹  Anum Mughal¹  Madiha Shareef²  Arshi Naz³  Muzaffar Umair Shah³  Safia Zafar Siddiqui¹ 

[1] Department of Anesthesiology, SICU and Pain Management, Dr. Ruth KM Pfau Civil Hospital;Department of Anesthesiology, Sindh Government Hospital;Department of Anesthesiology, Shaheed Mohtarmah Benazir Bhutto Institute of Trauma

关键词: Anesthesia;    Spinal;    Analgesia;    Obstetrical;    Analgesics;    Opioid;    Anesthetics;    Local;    Dexmedetomidine;    Double-Blind Method;    Female;    Humans;    Pain Measurement;    Pregnancy;   

DOI  :  10.35975/apic.v26i5.2019

学科分类：社会科学、人文和艺术（综合）

来源: THK

【 摘 要 】

Background & objectives: Spinal anesthesia is the preferred technique for obstetric patients as it is economical, simple to perform, has a rapid onset and provides complete muscle relaxation. A variety of adjuvants have been used to enhance or prolong its effects. We compared the effects of dexmedetomidine and fentanyl on the onset and recovery times of sensory and motor blockade as well as on hemodynamics, postoperative complications and duration of postoperative analgesia in parturients undergoing lower segment cesarean section (LSCS). Methodology: It was a prospective, double blind, randomized controlled trial. Sixty healthy parturients having cesarean delivery under spinal anesthesia were randomly divided into two equal groups. Group BD was given 10 mg bupivacaine plus 5 µg of dexmedetomidine and Group BF was given 10 mg bupivacaine plus 10 µg of fentanyl. Parturients was then observed for the onset and recovery times of sensorimotor blockade, hemodynamics, postoperative complications and postoperative analgesia.

【 授权许可】

CC BY-NC