Real-time Detection of Cellular Metabolism: a New Trend for Intra-Operative Diagnosis of Cavity Margins

Archives of Breast Cancer

article

Mohammad Abdolahad¹  Ahmad Kaviani² 

[1] Nano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran;Department of Surgical Oncology, University of Monntreal. Department of Surgery, Tehran Uiversity of Medical Sciences

关键词: Breast Cancer;    Intraoperative assessment;    Surgical Margin;    breast conserving surgery;   

DOI  :  10.32768/abc.20231011-3

学科分类：社会科学、人文和艺术（综合）

来源: Kaviani Breast Disease Institute

【 摘 要 】

During decades of breast cancer management, theclear surgical margin in breast cancer surgery hassaved its importance even after considerableimprovements in adjuvant therapies.1It has asignificant independent impact on the treatmentoutcome, especially the local control of the disease.2Traditionally, wide surgical margins (more than 2cm)were the standard of care in breast cancer surgery.Improving the surgical techniques, adding radiationas a local adjuvant therapy, systemic therapies such aschemotherapy, hormonal therapy and targetedtherapy allowed the surgeons to modify their surgicaltreatment to accept closer margins. Nowadays, “noink on tumor” for most invasive and 2mm safe marginfor in situ carcinomas (DCIS) are accepted accordingto most protocols and recommendations.

【 授权许可】

CC BY-NC