Breast Cancer Recurrence Survival Among Iranian Patients; A 17-Year Retrospective Cohort Study

Archives of Breast Cancer

article

Amirreza Ehsani¹  Nahid Nafissi¹  Mohammadamin Joulani²  Ebrahim Babaee³ 

[1] Department of Surgery, Iran University of Medical Sciences;Student Research Committee, Iran University of Medical Sciences;Department of Community and Family Medicine, School of Medicine, Iran University of Medical Science

关键词: Breast Cancer;    Recurrence;    Metastasis;    Survival;   

DOI  :  10.32768/abc.202184284-290

学科分类：社会科学、人文和艺术（综合）

来源: Kaviani Breast Disease Institute

【 摘 要 】

Background: Nowadays breast cancer (BC) is the most common cancer in women. More than 1.5 million cases are detected yearly. Survival of patients is dependent on several factors. Metastasis and cancer recurrence of different types and in different locations have various outcome.  Methods: This is a retrospective cohort study to describe survival of patients after diagnosis of breast cancer based on receptor subtypes and sites of metastasis among Iranian population. A total number of 2051 females with breast cancer were evaluated and among these, 138 patients with recurrent BC were investigated. Results: The 1-year survival of local, bone, visceral and brain metastasis were 64.99%, 63%, 32.83%, and 21.57%, respectively. Based on sites of metastasis, bone and local metastasis showed the best survival while brain and visceral metastasis had the worst survival and prognosis. Conclusion: Our study showed that Her2 enriched positive BCs had the worst survival, this may be due to Trastuzumab uncovered insurance till 10 years ago in our country. Also, drugs related to luminal A and B which are used to improve their survival and hormonal therapy could be associated with their better prognosis in comparison to triple negative receptor subtype. But this study showed that triple negative BC had better survival.

【 授权许可】

CC BY-NC