An Increased Lactate-to-pyruvate Ratio Is Not a Stand-alone Marker of Ischemia

Transplantation Direct

article

Håkon Haugaa¹  Pål-Dag Line²  Tor Inge Tønnessen¹ 

[1] Department of Anesthesia and Intensive Care, Oslo University Hospital and Lovisenberg Diaconal University College;Department of Transplantation Medicine, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo

DOI  :  10.1097/TXD.0000000000000991

学科分类：社会科学、人文和艺术（综合）

来源: Wolters Kluwer

【 摘 要 】

We read the article Evaluation of IntrahepaticLactate/Pyruvate Ratio As a Marker for IschemicComplications Early After Liver Transplantation—A ClinicalStudy authored by von Platen et al. 1 The authors concludethat the lactate-to-pyruvate ratio (L/Pr) is not a reliablemarker of ischemia in liver transplants and question the clinical utility of the cutoff values for detection of ischemia (lactate > 3 mmol/L) and L/Pr that we reported from a cohort of73 liver transplants in 2012,2 and which was followed up in areport on 20 pediatric liver transplants in 2013.

【 授权许可】

CC BY|CC BY-NC-ND