Nanotheranostics through Mitochondria-targeted Delivery with Fluorescent Peptidomimetic Nanohybrids for Apoptosis Induction of Brain Cancer Cells

Nanotheranostics

article

Isadora C. Carvalho¹  Alexandra A. P. Mansur¹  Sandhra M. Carvalho¹  Herman S. Mansur¹ 

[1] Center of Nanoscience, Nanotechnology, and Innovation - CeNano 2 I, Department of Metallurgical and Materials Engineering, Federal University of Minas Gerais - UFMG

关键词: nanoconjugates;    fluorescent nanoparticles;    dual-functional bioconjugates;    cancer nanomedicine;    dual-targeted drug delivery;   

DOI  :  10.7150/ntno.54491

学科分类：大气科学

来源: Ivyspring International Publisher

【 摘 要 】

Overview: Malignant brain tumors remain one of the greatest challenges faced by health professionals and scientists among the utmost lethal forms of cancer. Nanotheranostics can play a pivotal role in developing revolutionary nanoarchitectures with multifunctional and multimodal capabilities to fight cancer. Mitochondria are vital organelles to eukaryotic cells, which have been recognized as a significant target in cancer therapy where, by damaging the mitochondria, it will cause irreparable cell death or apoptosis.

【 授权许可】

CC BY-NC