COVID-19 and its Outcomes in Multiple Sclerosis Patients

Caspian Journal of Neurological Sciences

article

Masood Najafi¹  Sharareh Eskandarieh¹  Nasim Rezaeemanesh¹  Hora Heydari¹  Marzieh Moosavi²  Mohammad Hossein Harirchian² 

[1] Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences;Iranian Centre of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences

关键词: Multiple Sclerosis (MS);    Coronavirus Disease 2019 (COVID-19);    Epidemiology;   

DOI  :  10.32598/CJNS.8.29.5

学科分类：社会科学、人文和艺术（综合）

来源: Presses Agronomiques De Gembloux

【 摘 要 】

Background: Coronavirus Disease 2019 (COVID-19) is a highly contagious disease that resulted in 4533645 deaths until September first, 2021. Multiple Sclerosis (MS) patients receive immunosuppressive drugs. Thus, there is a concern that these drugs will reduce the patient’s immune system resistance against COVID19. Objectives: This study aimed to evaluate the epidemiology of COVID19 and its impact on MS patients in our university hospital in Tehran City, Iran. Materials & Methods: A cross-sectional study was conducted based on hospital-based registry data from May 2020 to March 2021. Among more than 500 registered MS patients in Imam Khomeini Hospital in Tehran City, Iran, referring within our study period, 84 patients reported SARS-COV2 infection. The diagnosis of MS was confirmed by the McDonald criteria. Moreover, the diagnosis of COVID-19 in MS patients was established by the real-time-PCR technique and chest computed tomography. Results: Out of 84 MS patients with SARS-COV2 infection, 55(65.5%) were women, and their mean age was 37.48 years. The most commonly used medications by MS patients were Rituximab 20 (26.3%) and Dimethyl Fumarate 14(18.4%). Totally, 9(10.8%) of the patients needed to be hospitalized due to COVID-19, with a mean hospitalization duration of 5.88 days. A total of 1 (1.2%) death was reported. Conclusion: Compared to the healthy population, COVID-19 is not more serious in MS patients. Most MS patients with COVID-19 infection were not hospitalized and continued their medication during the infection.

【 授权许可】

CC BY-NC