Osseointegration of retrieved 3D-printed, off-the-shelf acetabular implants

Bone & Joint Research

article

Lorenzo Dall’Ava¹  Harry Hothi²  Johann Henckel²  Anna Di Laura²  Roberto Tirabosco³  Antti Eskelinen⁴  John Skinner²  Alister Hart¹ 

[1] Institute of Orthopaedics and Musculoskeletal Science, Division of Surgery and Interventional Science, University College London;Royal National Orthopaedic Hospital NHS Trust;Department of Histopathology, Royal National Orthopaedic Hospital NHS Trust;The Coxa Hospital for Joint Replacement

关键词: 3D-printing;    Additive manufacturing;    Osseointegration;    Hip arthroplasty;    Retrieval analysis;   

DOI  :  10.1302/2046-3758.107.BJR-2020-0462.R1

学科分类：骨科学

来源: British Editorial Society Of Bone And Joint Surgery

【 摘 要 】

AimsThe main advantage of 3D-printed, off-the-shelf acetabular implants is the potential to promote enhanced bony fixation due to their controllable porous structure. In this study we investigated the extent of osseointegration in retrieved 3D-printed acetabular implants.MethodsWe compared two groups, one made via 3D-printing (n = 7) and the other using conventional techniques (n = 7). We collected implant details, type of surgery and removal technique, patient demographics, and clinical history. Bone integration was assessed by macroscopic visual analysis, followed by sectioning to allow undecalcified histology on eight sections (~200 µm) for each implant. The outcome measures considered were area of bone attachment (%), extent of bone ingrowth (%), bone-implant contact (%), and depth of ingrowth (%), and these were quantified using a line-intercept method.Results0.152). There was no difference in visual bony attachment (p = 0.209). Histological analysis showed greater bone ingrowth in 3D-printed implants (p < 0.001), with mean bone attachment of 63% (SD 28%) and 37% (SD 20%), respectively. This was observed for all the outcome measures.ConclusionThis was the first study to investigate osseointegration in retrieved 3D-printed acetabular implants. Greater bone ingrowth was found in 3D-printed implants, suggesting that better osseointegration can be achieved. However, the influence of specific surgeon, implant, and patient factors needs to be considered.

【 授权许可】

CC BY-NC