Use of Stimulan absorbable calcium sulphate beads in revision lower limb arthroplasty: Safety profile and complication rates

Bone & Joint Research

article

R. Kallala¹  W. Edwin Harris²  M. Ibrahim³  M. Dipane⁴  E. McPherson⁴ 

[1] Epsom and St Helier Hospitals NHS Trust;Manchester Metropolitan University;University College Hospital London;UCLA Medical Center, Santa Monica David Geffen School of Medicine at UCLA

关键词: Biomaterials;    Synthetic bone substitutes;    Calcium Sulphate;   

DOI  :  10.1302/2046-3758.710.BJR-2017-0319.R1

学科分类：骨科学

来源: British Editorial Society Of Bone And Joint Surgery

【 摘 要 】

AimsCalcium sulphate has traditionally been used as a filler of dead space arising during surgery. Various complications have been described following the use of Stimulan bio-absorbable calcium sulphate beads. This study is a prospective observational study to assess the safety profile of these beads when used in revision arthroplasty, comparing the complication rates with those reported in the literature.MethodsA total of 755 patients who underwent 456 revision total knee arthroplasties (TKA) and 299 revision total hip arthroplasties (THA), with a mean follow-up of 35 months (0 to 78) were included in the study.ResultsA total of 32 patients (4.2%) had wound drainage, and this was higher with higher bead volumes and in McPherson grade C patients. There was also a significantly higher bead volume in the 41 patients who developed hypercalcaemia, two of which were symptomatic (p 0.05).ConclusionThe strength of this study lies in the large number of patients and the detailed data collection, making it the most comprehensive report available in the literature on the use of calcium sulphate-based bone substitutes.

【 授权许可】

CC BY-NC