Influence of droplet coverage on the electrochemical response of planar microelectrodes and potential solving strategies based on nesting concept

PeerJ

article

Yue Yu¹  Zhanming Li¹ 

[1] Department of Biosystems Engineering, Zhejiang University;Department of Food Science, College of Life Science, China Jiliang University

关键词: Droplet coverage;    Three dimensional (3D) printing;    Signal change;    Screen-printed interdigitated microelectrode (SPIM);    Nest-like;    Electrochemical response;   

DOI  :  10.7717/peerj.2400

学科分类：社会科学、人文和艺术（综合）

来源: Inra

【 摘 要 】

Recently, biosensors have been widely used for the detection of bacteria, viruses and other toxins. Electrodes, as commonly used transducers, are a vital part of electrochemical biosensors. The coverage of the droplets can change significantly based on the hydrophobicity of the microelectrode surface materials. In the present research, screen-printed interdigitated microelectrodes (SPIMs), as one type of planar microelectrode, were applied to investigate the influence of droplet coverage on electrochemical response. Furthermore, three dimensional (3D) printing technology was employed to print smart devices with different diameters based on the nesting concept. Theoretical explanations were proposed to elucidate the influence of the droplet coverage on the electrochemical response. 3D-printed ring devices were used to incubate the SPIMs and the analytical performances of the SPIMs were tested. According to the results obtained, our device successfully improved the stability of the signal responses and eliminated irregular signal changes to a large extent. Our proposed method based on the nesting concept provides a promising method for the fabrication of stable electrochemical biosensors. We also introduced two types of electrode bases to improve the signal stability.

【 授权许可】

CC BY