PeerJ | |
Public perception of the vegetative state/unresponsive wakefulness syndrome: a crowdsourced study | |
article | |
Daniel Kondziella1  Man Cheung Cheung4  Anirban Dutta4  | |
[1] Department of Neurology, Rigshospitalet, Copenhagen University Hospital;Faculty of Health and Medical Sciences, University of Copenhagen;Department of Neuroscience, Norwegian University of Science and Technology;Department of Biomedical Engineering, University at Buffalo, The State University of New York | |
关键词: Consciousness; Coma; Neurorehabilitation; Traumatic brain injury; Disorders of consciousness; Ethics; Cognitive motor dissociation; Brain injury; Locked-in syndrome; Intensive care; | |
DOI : 10.7717/peerj.6575 | |
学科分类:社会科学、人文和艺术(综合) | |
来源: Inra | |
【 摘 要 】
BackgroundThe vegetative state (VS)/unresponsive wakefulness syndrome (UWS) denotes brain-injured, awake patients who are seemingly without awareness. Still, up to 15% of these patients show signs of covert consciousness when examined by functional magnetic resonance imaging (fMRI) or EEG, which is known as cognitive motor dissociation (CMD). Experts often prefer the term unresponsive wakefulness syndrome to avoid the negative connotations associated with vegetative state and to highlight the possibility for CMD. However, the perception of VS/UWS by the public has never been studied systematically.MethodsUsing an online crowdsourcing platform, we recruited 1,297 lay people from 32 countries. We investigated if vegetative state and unresponsive wakefulness syndrome might have a different influence on attitudes towards VS/UWS and the concept of CMD.ResultsParticipants randomized to be inquired about the vegetative state believed that CMD was less plausible (mean estimated frequency in unresponsive patients 38.07% ± SD 25.15) than participants randomized to unresponsive wakefulness syndrome (42.29% ± SD 26.63; Cohen’s d 0.164; p = 0.016). Attitudes towards treatment withdrawal were similar. Most participants preferred unresponsive wakefulness syndrome (60.05%), although a sizeable minority favored vegetative state (24.21%; difference 35.84%, 95% CI 29.36 to 41.87; p < 0.0001). Searches on PubMed and Google Trends revealed that unresponsive wakefulness syndrome is increasingly used by academics but not lay people.DiscussionSimply replacing vegetative state with unresponsive wakefulness syndrome may not be fully appropriate given that one of four prefer the first term. We suggest that physicians take advantage of the controversy around the terminology to explain relatives the concept of CMD and its ethical implications.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202307100010821ZK.pdf | 1397KB | download |