The effect of lip closure on palatal growth in patients with unilateral clefts

PeerJ

article

Robin Bruggink¹  Frank Baan¹  Gem Kramer⁴  Colet Claessens²  Anne Marie Kuijpers-Jagtman⁵  Ewald M. Bronkhorst⁸  Thomas J.J. Maal¹  Edwin Ongkosuwito² 

[1] Department of Dentistry - Orthodontics and Craniofacial Biology, Radboud University Medical Center;Radboudumc 3DLab, Radboud University Medical Center;Radboud Institute for Health Sciences, Radboud University Medical Center;“Alkmaarse Orthodontisten”;Department of Orthodontics, University Medical Center Groningen;Department of Orthodontics and Dentofacial Orthopedics, University of Bern;Faculity of Dentistry, Universitas Indonesia;Department of Dentistry - Preventive and Restorative Dentistry, Radboud University Medical Center;Department of Oral and Maxillofacial Surgery, Radboud University Medical Center;Amalia Cleft and Craniofacial centre, Radboud University Medical Center

关键词: Orthodontics;    Dental models;    Imaging;    Three-Dimensional;    Cleft palate;    Diagnostic imaging;    Maxillofacial development;   

DOI  :  10.7717/peerj.9631

学科分类：社会科学、人文和艺术（综合）

来源: Inra

【 摘 要 】

ObjectivesThe objective of this study was to compare maxillary dimensions and growth in newborns with Complete Unilateral Cleft Lip and Palate (UCLP) to healthy newborns before and after cheiloplasty. Additionally, a palatal growth curve is constructed to give more information about the natural growth before surgical intervention.MethodsTwenty-eight newborns with complete UCLP were enrolled in this study. Multiple plaster-casts of each child during their first year were collected and grouped in before and after cheiloplasty. A previous developed semi-automatic segmentation tool was used to assess the maxillary dimensions and were compared to a healthy control group. Z-scores were calculated to indicate differences between the two populations and if cheiloplasty had influence on maxillary growth. Furthermore, the prediction model created in a previous study was used to indicate differences between predictions and the outcome in UCLP measurements. The analysis was tested for inter- and intra-observer variability.ResultsResults show differences in alveolar and palatal shape in UCLP patients in comparison with healthy controls. Prior to cheiloplasty an increased width and alveolar length was observed while the palatal depth was decreased. After cheiloplasty the widths moved towards normal but were still significantly larger.ConclusionInfants with unilateral cleft lip and palate show a wider maxillary arch in comparison with the control population. Initial treatment has most influence on the width of the arch, which decreased towards normal.

【 授权许可】

CC BY