Detection and estimating the blood accumulation volume of brain hemorrhage in a human anatomical skull using a RF single coil

PeerJ

article

Moshe Oziel¹  Boris Rubinsky²  Rafi Korenstein¹ 

[1] Department of Physiology and Pharmacology, Tel-Aviv University;Department of Mechanical Engineering, University of California

关键词: Hematoma;    Inductive coil;    Monitoring;    Non-contact;    Radiofrequency;   

DOI  :  10.7717/peerj.10416

学科分类：社会科学、人文和艺术（综合）

来源: Inra

【 摘 要 】

Objective An experimental study for testing a simple robust algorithm on data derived from an electromagnetic radiation device that can detect small changes in the tissue/fluid ratio in a realistic head configuration. Methods Changes in the scattering parameters (S21) of an inductive coil resulting from injections of chicken blood in the 0–18 ml range into calf brain tissue in a human anatomical skull were measured over a 100–1,000 MHz frequency range. Results An algorithm that combines amplitude and phase results was found to detect changes in the tissue/fluid ratio with 90% accuracy. An algorithm that estimated the injected blood volume was found to have a 1–4 ml average error. This demonstrates the possibility of the inductive coil-based device to possess a practical ability to detect a change in the tissue/fluid ratio in the head. Significance This study is an important step towards the goal of building an inexpensive and safe device that can detect an early brain hemorrhagic stroke.

【 授权许可】

CC BY