A preliminary comparative study of percutaneous CT-guided cryoablation with surgical resection for osteoid osteoma

PeerJ

article

Liangliang Meng¹  Xiao Zhang²  Ruijiang Xu⁴  Bin Wu³  Xiaobo Zhang²  Yingtian Wei²  Jing Li²  Husheng Shan²  Yueyong Xiao² 

[1] Medical School of Chinese PLA;Department of Radiology, the First Medical Centre, Chinese PLA General Hospital;Department of Radiology, Chinese PAP Beijing Corps Hospital;Department of Pediatric Surgery, Chinese PLA General Hospital

关键词: Cryoablation;    Osteoid osteoma;    Surgery;    Computed tomography;   

DOI  :  10.7717/peerj.10724

学科分类：社会科学、人文和艺术（综合）

来源: Inra

【 摘 要 】

BackgroundThe traditional treatment for osteoid osteoma is the nidus’ surgical resection, which was difficult to eradicate with more invasive and complications because of osteosclerosis surrounding the nidus. This study aimed to analyze the efficacy and safety of percutaneous CT-guided cryoablation of osteoid osteoma at different sites (especially refractory sites such as the spine).MethodsFifteen patients with osteoid osteoma who underwent cryoablation at our institution were analyzed retrospectively on their imaging data and clinical visual analog scale (VAS) pain scores before and after the procedure. Fifty-three patients underwent surgical resection during the period were also included in this study as a control group. Treatment efficacy was assessed primarily by comparing the differences in VAS scores at different time points in each group of patients by paired-sample t-test. Differences in length of hospital stay and complications between the two groups were also compared.ResultsThe technical success rate was 100% in both the cryoablation and surgical resection group. Cryoablation had a significantly shorter hospitalization time than surgery (p500 ml), and two underwent transfusion therapy. Only one patient in the surgical resection group experienced a recurrence at 29 months postoperatively and underwent a second resection. All patients had local scars on the skin after surgical resection.ConclusionCryoablation is a minimally invasive, safe, and effective treatment strategy for osteoid osteoma, and is fully comparable to surgical resection.

【 授权许可】

CC BY