Outcomes of hospitalized patients with COVID-19 according to level of frailty

PeerJ

article

Eva María Andrés-Esteban¹  Manuel Quintana-Diaz¹  Karen Lizzette Ramírez-Cervantes¹  Irene Benayas-Peña¹  Alberto Silva-Obregón¹  Rosa Magallón-Botaya⁶  Ivan Santolalla-Arnedo⁷  Raúl Juárez-Vela¹  Vicente Gea-Caballero⁸ 

[1] Grupo PBM, Instituto de Investigación-IdiPaz;Universidad Rey Juan Carlos;Servicio de Medicina Intensiva, Hospital Universitario La Paz;Departamento de Prevención;Servicio de Medicina Intensiva, Hospital Universitario de Guadalajara;Departamento de Medicina, Psiquiatría y Dermatología, Universidad de Zaragoza;Universidad de La Rioja;Nursing School La Fe., Adscript center of Universidad de Valencia.;Research Group GREIACC, Health Research Institute La Fe.

关键词: Aged;    COVID-19;    SARS-CoV-2;    Frailty;    Mortality;    Coronavirus infection;    Complications;    Prognosis;   

DOI  :  10.7717/peerj.11260

学科分类：社会科学、人文和艺术（综合）

来源: Inra

【 摘 要 】

Background The complications from coronavirus disease 2019 (COVID-19) have been the subject of study in diverse scientific reports. However, many aspects that influence the prognosis of the disease are still unknown, such as frailty, which inherently reduces resistance to disease and makes people more vulnerable. This study aimed to explore the complications of COVID-19 in patients admitted to a third-level hospital and to evaluate the relationship between these complications and frailty. Methods An observational, descriptive, prospective study was performed in 2020. A sample of 254 patients from a database of 3,112 patients admitted to a high-level hospital in Madrid, Spain was analyzed. To assess frailty (independent variable) the Clinical Frailty Scale (CFS) was used. The outcome variables were sociodemographic and clinical, which included complications, length of stay, intensive care unit (ICU) admission and prognosis. Results A total of 13.39% of the patients were pre-frail and 17.32% were frail. Frail individuals had a shorter hospital stay, less ICU admission, higher mortality and delirium, with statistical significance. Conclusion Frailty assessment is a crucial approach in patients with COVID-19, given a higher mortality rate has been demonstrated amongst frail patients. The CFS could be a predictor of mortality in COVID-19.

【 授权许可】

CC BY