期刊论文详细信息
PeerJ
Depression and low physical activity are related to sarcopenia in hemodialysis: a single-center study
article
Kornanong Yuenyongchaiwat1  Sasikan Jongritthiporn1  Kasarn Somsamarn1  Oranat Sukkho1  Sasipim Pairojkittrakul3  Opas Traitanon4 
[1] Department of Physiotherapy/ Faculty of Allied Health Sciences, Thammasat University;Thammasat University, Research Unit in Physical Therapy in Respiratory and Cardiovascular Systems;Nephrology Clinic, Thammasat University Hospital;Division of Nephrology, Department of Internal medicine, Faculty of Medicine, Thammasat University
关键词: Physical activity;    Depression;    Sarcopenia;    Hemodialysis;    Prevalence;   
DOI  :  10.7717/peerj.11695
学科分类:社会科学、人文和艺术(综合)
来源: Inra
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【 摘 要 】

BackgroundThe number of patients who suffer from chronic renal failure (CRF) has widely increased worldwide. Patients with advanced stages of CRF experience a gradual and progressive loss of muscle and fat mass leading to decreased physical activity and mental health problems. The loss of muscle mass in CRF might contribute to the development of sarcopenia. Therefore, this study aimed to explore the prevalence of sarcopenia and to determine the relationship of physical activity and mental state of depression with sarcopenia in hemodialysis patients.MethodsA cross-sectional study was designed with a total of 104 male and female with a minimum age of 35 years. Based on the guidelines of the Asian Working Group for Sarcopenia in 2019, gait speed, muscle mass, and handgrip were used to define sarcopenia. In addition, participants were requested to perform a set of questionnaires to evaluate their physical activity and state of depression. Logistic regression analyses were used to explore the risk factors of sarcopenia.ResultsThirty-four (32.69%) of 104 participants had sarcopenia. Compared to the 70 individuals without sarcopenia, they had a low physical activity and a high depression score (ps < .05). Furthermore, low physical activity and high depression scores in combination with sarcopenia were associated with an increased mortality risk. Low physical activity and high depression scores were also independently associated with sarcopenia in hemodialysis patients after controlling for age (odds ratio = 3.23, and 4.92, respectively).

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