Sarcopenia is not associated with inspiratory muscle strength but with expiratory muscle strength among older adults requiring long-term care/support

PeerJ

article

Yohei Sawaya¹  Takahiro Shiba²  Masahiro Ishizaka¹  Tamaki Hirose¹  Ryo Sato²  Akira Kubo¹  Tomohiko Urano² 

[1]Department of Physical Therapy, School of Health Sciences, International University of Health and Welfare

[2]Nishinasuno General Home Care Center, Department of Day Rehabilitation

[3]Department of Geriatric Medicine, School of Medicine, International University of Health and Welfare

关键词: Elderly;    Respiratory muscles;    Respiratory sarcopenia;    Spirometry;    Maximal expiratory pressure;   

DOI  :  10.7717/peerj.12958

学科分类：社会科学、人文和艺术（综合）

来源: Inra

【 摘 要 】

Background Recently, the concept of respiratory sarcopenia has been advocated, but evidence is lacking regarding which respiratory parameters are appropriate indicators. Therefore, we investigated the association between sarcopenia, respiratory function, and respiratory muscle strength to identify the most appropriate parameters for respiratory sarcopenia. Methods We included 124 older adults (67 men, 57 women; average age 77.2 ± 8.3 years) requiring long-term care/support who underwent Day Care for rehabilitation. Handgrip strength, usual gait speed, and skeletal muscle mass were measured using bioelectrical impedance analysis. Participants were then diagnosed with sarcopenia using the algorithm of the Asian Working Group for Sarcopenia 2019. Parameters of respiratory function (forced vital capacity, forced expiratory volume in one second [FEV1.0], FEV1.0%, and peak expiratory flow rate) and respiratory muscle strength (maximal expiratory pressure [MEP] and maximal inspiratory pressure) were also measured according to American Thoracic Society guidelines. Respiratory parameters significantly related to sarcopenia were identified using binomial logistic regression and receiver operating characteristic analyses. Results Seventy-seven participants were classified as having sarcopenia. Binomial logistic regression analysis showed that MEP was the only respiratory parameter significantly associated with sarcopenia. The cut-off MEP value for predicting sarcopenia was 47.0 cmH20 for men and 40.9 cmH20 for women. Conclusions The most appropriate parameter for assessing respiratory sarcopenia may be MEP, which is an indicator of expiratory muscle strength, rather than FVC, MIP, or PEFR, as suggested in previous studies. Measuring MEP is simpler than measuring respiratory function parameters. Moreover, it is expected to have clinical applications such as respiratory sarcopenia screening.

【 授权许可】

CC BY