Genome-wide survey of HMA gene family and its characterization in wheat ( Triticum aestivum )

PeerJ

article

Sadaf Zahra¹  Tayyaba Shaheen¹  Muhammad Qasim¹  Mahmood-ur-Rahman¹  Momina Hussain²  Sana Zulfiqar³  Kanval Shaukat⁴  Mehboob-ur-Rahman³ 

[1] Department of Bioinformatics and Biotechnology, Government College University, Faisalabad;Department of Biotechnology, Faculty of Life Sciences, University of Okara;Plant Genomics and Molecular Breeding Laboratory, National Institute for Biotechnology and Genetic Engineering College, Pakistan Institute of Engineering and Applied Sciences ,(NIBGE-C, PIEAS), Faisalabad;Department of Botany, University of Balochistan

关键词: Bioinformatics;    Genome-wide analysis;    Heavy metal toxicity;    HMA gene family;    Phylogenetic analysis;   

DOI  :  10.7717/peerj.14920

学科分类：社会科学、人文和艺术（综合）

来源: Inra

【 摘 要 】

Background Abiotic stresses, particularly drought and heavy metal toxicity, have presented a significant risk to long-term agricultural output around the world. Although the heavy-metal-associated domain (HMA) gene family has been widely explored in Arabidopsis and other plants, it has not been thoroughly studied in wheat (Triticum aestivum). This study was proposed to investigate the HMA gene family in wheat. Methods To analyze the phylogenetic relationships, gene structure, gene ontology, and conserved motifs, a comparative study of wheat HMA genes with the Arabidopsis genome was performed. Results A total of 27 T. aestivum proteins belonging to the HMA gene family were identified in this study, with amino acid counts ranging from 262 to 1,071. HMA proteins were found to be grouped into three subgroups in a phylogenetic tree, and closely related proteins in the tree showed the same expression patterns as motifs found in distinct subgroups. Gene structural study elucidated that intron and exon arrangement differed by family. Conclusion As a result, the current work offered important information regarding HMA family genes in the T. aestivum genome, which will be valuable in understanding their putative functions in other wheat species.

【 授权许可】

CC BY