Histological evaluation of the synergistic effect of chitosan and mineral trioxide aggregate on mechanically exposed dental pulp following pulp capping in dogs' teeth

Saudi Endodontic Journal

article

Ramy A. Emara¹  Ashraf M. Abu-Seida²  Salma H.El Ashry¹ 

[1] Department of Endodontic, Faculty of Dentistry, Ain Shams University;Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Cairo University

关键词: Capping material;    dental pulp;    dentin bridge;    dog's teeth;    odontogenesis;   

DOI  :  10.4103/sej.sej_294_20

学科分类：口腔科学

来源: Medknow

【 摘 要 】

Introduction: This work studied the synergistic effect of chitosan and mineral trioxide aggregate (MTA) on mechanically exposed dental pulp following pulp capping in dogs' teeth. Materials and Methods: Class V cavities were prepared in 60 teeth of 3 mongrel dogs. These cavities were prepared approximately 1 mm coronal to the gingival margin by using a round carbide bur #2 with water cooling. These teeth were divided according to the pulp capping material into 2 groups (30 teeth each); Group I: MTA and Group II: a combination of MTA and chitosan compound. The cavities were restored by self-curing glass ionomer cement, followed by varnish application to provide the suitable conditions for pulpal repair. Both groups were further subdivided according to the evaluation period into 3 subgroups (10 teeth each); subgroup A: 7 days, subgroup B: 21 days, and subgroup C: 60 days. Histological evaluation of dentin bridge formation was performed after pulp capping in all subgroups. Data were statistically analyzed by ANOVA, Tukey's post hoc, Kruskal–Wallis, and Mann–Whitney U-tests. The significance level was set at P ≤ 0.05. Results: No statistically significant difference was found between both groups at all evaluation times (P 0.05). The combination of MTA and chitosan did not improve the quality of dentin bridge produced by the MTA alone. Conclusion: Mixing of chitosan and MTA as a direct pulp capping material has no synergistic odontogenic effect in dog's teeth.

【 授权许可】

CC BY-NC-SA