Anticoagulant status under COVID-19: The potential pathophysiological mechanism

Journal of Applied Hematology

article

Basheer Abdullah Marzoog¹ 

[1] Medical School Student at National Research Mordovia State University

关键词: Anticoagulant;    coagulopathy;    coronavirus disease 19;    hemostasis;    homeostasis;    pathogenesis;    pulmonary embolism;    severe acute respiratory syndrome coronavirus disease 2;    thrombosis;   

DOI  :  10.4103/joah.joah_154_21

学科分类：社会科学、人文和艺术（综合）

来源: Medknow

【 摘 要 】

Coronavirus disease 19 (COVID-19) is a systematic multitropic disease. Sustaining blood homeostasis is a mission of multiple factors includes procoagulant and anticoagulant systems. Subsequently, maintaining a precise equilibrium between these antagonists' systems is crucial to prevent hemostasis. Frequently, during severe forms of COVID-19 patients, studies reported a discrepancy between the procoagulant and anticoagulant that usually results in fatal outcomes through multiorgan ischemia by thrombotic events. The proper interpreting of the anticoagulant status changes in COVID-19 patients is sufficient for effective and safe anticoagulant treatment. Our postulation is the first to address the pathophysiology of anticoagulant status under COVID-19.

【 授权许可】

CC BY-NC-SA