The Neutrophil-to-Lymphocyte Ratio’s Predictive Utility in Acute Pulmonary Embolism: Systematic Review

Journal Of Cardiovascular Emergencies

article

Emil Marian Arbănași¹  Adrian Vasile Mureșan¹  Eliza Mihaela Arbănași³  Réka Kaller¹  Ioana Iulia Cojocaru²  Cătălin Mircea Coșarcă¹  Eliza Russu¹ 

[1]Clinic of Vascular Surgery, Mureș County Emergency Hospital

[2]Department of Surgery, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology

[3]Faculty of Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology

[4]Department of Anatomy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology

关键词: neutrophil-to-lymphocyte ratio;    acute pulmonary embolism;    mortality rate;    inflammatory markers;    NLR cut-off value;   

DOI  :  10.2478/jce-2022-0005

学科分类：社会科学、人文和艺术（综合）

来源: Walter de Gruyter GmbH

【 摘 要 】

Acute pulmonary embolism is a cardiovascular emergency with a significant morbidity and mortality. In the last decade, attempts have been made to find prognostic markers for pulmonary embolism. We conducted a systematic review of the literature for studies that assess the relationship between the neutrophil-to-lymphocyte ratio (NLR) and disease progression in patients with pulmonary embolism. We included a total of seven studies published between 2016 and 2021, reporting on a total of 4,272 patients. The mean NLR observed in these studies was 5.93, with values ranging from 5.12 to 7.3. Elevated NLR was significantly associated with an increased rate of mortality in all studies. Furthermore, the collected data revealed a 2-to-15 times higher mortality rate in the group with NLR values higher than the mean. Due to its accessibility and the simplicity with which it can be calculated, as well as the outcomes revealed in this review, we strongly emphasize that NLR should be used more in medical practice.

【 授权许可】

CC BY-NC-ND