Interim analysis report of kuanxiong aerosol in improving angina and quality of life after percutaneous coronary intervention

World Journal of Traditional Chinese Medicine

article

Luo-Qi Lin¹  Bing-Xin Wu¹  Miao-Yang Lin¹  Qiu-Xiong Chen²  Dan-Ping Xu³ 

[1] The Second Clinical Medical College, Guangzhou University of Chinese Medicine;Department of Cardiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine;Department of Cardiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Postdoctoral Research Station, Institute of Integrative Chinese and Western Medicine, Fujian University of Traditional Chinese Medicine

关键词: Angina;    Kuanxiong aerosol;    percutaneous coronary intervention;    quality of life;   

DOI  :  10.4103/wjtcm.wjtcm_26_21

学科分类：内科医学

来源: Wolters Kluwer Medknow Publications

【 摘 要 】

Objective: The objective is to observe the effect of Kuanxiong aerosol (KXA) on angina and the quality of life of patients after percutaneous coronary intervention (PCI). Materials and Methods: Six hundred patients with angina after PCI (AAP) were randomly assigned to an experimental group and a control group ( n = 300 in each group) and received basic treatment with KXA or basic treatment (respectively) for 8 weeks. The Seattle Angina Questionnaire (SAQ) and visual analog scale (VAS) scores of the two groups during the screening period and five follow-up periods were compared. Results: A total of 179 patients were included in this interim report, including 85 in the experimental group and 94 in the control group. Among the five-dimensional scores of the SAQ, the improvement in the angina frequency and quality of life scores in the experimental group was better than those in the control group after treatment ( P < 0.01), and the difference in scores of the remaining dimensions was not statistically significant ( P > 0.01). The difference in VAS scores between the two groups was not statistically significant ( P > 0.01). No obvious adverse reactions were observed between the two groups. Conclusions: KXA can reduce the frequency of AAP and improve patients' quality of life.

【 授权许可】

CC BY-NC-SA