Oxytocin improves testicular blood flow without enhancing the steroidogenic activity in Baladi goats

Asian Pacific Journal of Reproduction

article

Hedia, Mohamed G.¹  El-Shalofy, Amr S.¹ 

[1] Department of Theriogenology, Faculty of Veterinary Medicine, Cairo University

关键词: Bucks;    Blood flow;    Doppler;    Estradiol-17β;    Goat;    Oxytocin;    Testicular artery;    Testosterone;   

DOI  :  10.4103/2305-0500.356841

学科分类：兽医学

来源: Wolters Kluwer Medknow Publications

【 摘 要 】

Objective:  To investigate the effects of a single oxytocin injection on plasma steroid concentrations, testicular blood flow measures (resistive and pulsatility indexes), and testicular echogenicity in Baladi goats. Methods:  Twelve Baladi goat bucks were randomly allocated into 2 groups and received an intravenous injection of either 0.7 IU/kg oxytocin or normal saline 0.9%. Venous blood samples were collected, and testicular blood flow Doppler parameters (i.e, peak systolic velocity, end-diastolic velocity, time average maximum velocity, resistive index, and pulsatility index) were assessed for supratesticular arteries in the left and right testes immediately before (0), and at 5, 30, 60, and 120 min after injection. Results:  Plasma concentrations of testosterone significantly decreased in the oxytocin0.05). Both resistive index and pulsatility index declined in the oxytocin group at 60 min posttreatment compared to the control group (P<0.05). Testicular pixel intensity increased at 30 min post-treatment in the oxytocin group compared to the control group (P<0.05). Conclusions:  Oxytocin treatment significantly increases testicular blood flow and decreases plasma testosterone concentrations in male Baladi goats.

【 授权许可】

CC BY-NC-SA